Amacher DE - Search Results

1

Induction of hepatic microsomal drug-metabolizing enzymes by inhibitors of 5-lipoxygenase (5-LO): studies in rats and 5-LO knockout mice.

Beierschmitt WP, McNeish JD, Griffiths RJ, Nagahisa A, Nakane M, Amacher DE. Beierschmitt WP, et al. Among authors: amacher de. Toxicol Sci. 2001 Sep;63(1):15-21. doi: 10.1093/toxsci/63.1.15. Toxicol Sci. 2001. PMID: 11509739

2

Hepatic microsomal enzyme induction, beta-oxidation, and cell proliferation following administration of clofibrate, gemfibrozil, or bezafibrate in the CD rat.

Amacher DE, Beck R, Schomaker SJ, Kenny CV. Amacher DE, et al. Toxicol Appl Pharmacol. 1997 Jan;142(1):143-50. doi: 10.1006/taap.1996.8007. Toxicol Appl Pharmacol. 1997. PMID: 9007043

3

The relationship among microsomal enzyme induction, liver weight and histological change in rat toxicology studies.

Amacher DE, Schomaker SJ, Burkhardt JE. Amacher DE, et al. Food Chem Toxicol. 1998 Sep-Oct;36(9-10):831-9. doi: 10.1016/s0278-6915(98)00066-0. Food Chem Toxicol. 1998. PMID: 9737431

4

The relationship among microsomal enzyme induction, liver weight, and histological change in cynomolgus monkey toxicology studies.

Amacher DE, Schomaker SJ, Boldt SE, Mirsky M. Amacher DE, et al. Food Chem Toxicol. 2006 Apr;44(4):528-37. doi: 10.1016/j.fct.2005.08.027. Epub 2005 Nov 7. Food Chem Toxicol. 2006. PMID: 16274908

5

Ethylmorphine N-demethylase activity as a marker for cytochrome P450 CYP3A activity in rat hepatic microsomes.

Amacher DE, Schomaker SJ. Amacher DE, et al. Toxicol Lett. 1998 Jan 31;94(2):115-25. doi: 10.1016/s0378-4274(97)00108-2. Toxicol Lett. 1998. PMID: 9574808

6

The relationship among microsomal enzyme induction, liver weight and histological change in beagle dog toxicology studies.

Amacher DE, Schomaker SJ, Burkhardt JE. Amacher DE, et al. Food Chem Toxicol. 2001 Aug;39(8):817-25. doi: 10.1016/s0278-6915(01)00030-8. Food Chem Toxicol. 2001. PMID: 11434989

7

BALB/c mice orally pretreated with diclofenac have augmented and accelerated PLNA responses to diclofenac.

Gutting BW, Updyke LW, Amacher DE. Gutting BW, et al. Among authors: amacher de. Toxicology. 2002 Apr 2;172(3):217-30. doi: 10.1016/s0300-483x(02)00008-2. Toxicology. 2002. PMID: 11893420

8

A comparison of the direct and reporter antigen popliteal lymph node assay for the detection of immunomodulation by low molecular weight compounds.

Gutting BW, Schomaker SJ, Kaplan AH, Amacher DE. Gutting BW, et al. Among authors: amacher de. Toxicol Sci. 1999 Sep;51(1):71-9. doi: 10.1093/toxsci/51.1.71. Toxicol Sci. 1999. PMID: 10496678

9

A Toxicologist's Guide to the Preclinical Assessment of Hepatic Microsomal Enzyme Induction.

Amacher DE. Amacher DE. Toxicol Mech Methods. 2006;16(7):385-94. doi: 10.1080/15376510600783791. Toxicol Mech Methods. 2006. PMID: 20021012

10

The early effects of short-term dexamethasone administration on hepatic and serum alanine aminotransferase in the rat.

Jackson ER, Kilroy C, Joslin DL, Schomaker SJ, Pruimboom-Brees I, Amacher DE. Jackson ER, et al. Among authors: amacher de. Drug Chem Toxicol. 2008;31(4):427-45. doi: 10.1080/01480540802390247. Drug Chem Toxicol. 2008. PMID: 18850354

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