Nagahisa A - Search Results

1

Induction of hepatic microsomal drug-metabolizing enzymes by inhibitors of 5-lipoxygenase (5-LO): studies in rats and 5-LO knockout mice.

Beierschmitt WP, McNeish JD, Griffiths RJ, Nagahisa A, Nakane M, Amacher DE. Beierschmitt WP, et al. Among authors: nagahisa a. Toxicol Sci. 2001 Sep;63(1):15-21. doi: 10.1093/toxsci/63.1.15. Toxicol Sci. 2001. PMID: 11509739

2

Tenidap inhibits 5-lipoxygenase product formation in vitro, but this activity is not observed in three animal models.

Carty TJ, Sweeney FJ, Griffiths RJ, Eskra JD, Ernest MJ, Pillar JS, Cheng JD, Loose LD, Joseph PA, Pazoles PP, Moore PF, Nagahisa A, Murase S, Kadin SB. Carty TJ, et al. Among authors: nagahisa a. Inflamm Res. 1997 May;46(5):168-79. doi: 10.1007/s000110050163. Inflamm Res. 1997. PMID: 9197987

3

Synthesis and structure-activity relationships of CP-122,721, a second-generation NK-1 receptor antagonist.

Rosen TJ, Coffman KJ, McLean S, Crawford RT, Bryce DK, Gohda Y, Tsuchiya M, Nagahisa A, Nakane M, Lowe JA 3rd. Rosen TJ, et al. Among authors: nagahisa a. Bioorg Med Chem Lett. 1998 Feb 3;8(3):281-4. doi: 10.1016/s0960-894x(98)00012-2. Bioorg Med Chem Lett. 1998. PMID: 9871670

4

Adenosine kinase inhibitors. 6. Synthesis, water solubility, and antinociceptive activity of 5-phenyl-7-(5-deoxy-beta-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidines substituted at C4 with glycinamides and related compounds.

Bookser BC, Ugarkar BG, Matelich MC, Lemus RH, Allan M, Tsuchiya M, Nakane M, Nagahisa A, Wiesner JB, Erion MD. Bookser BC, et al. Among authors: nagahisa a. J Med Chem. 2005 Dec 1;48(24):7808-20. doi: 10.1021/jm050394a. J Med Chem. 2005. PMID: 16302820

5

Adenosine kinase inhibitors. 5. Synthesis, enzyme inhibition, and analgesic activity of diaryl-erythro-furanosyltubercidin analogues.

Boyer SH, Ugarkar BG, Solbach J, Kopcho J, Matelich MC, Ollis K, Gomez-Galeno JE, Mendonca R, Tsuchiya M, Nagahisa A, Nakane M, Wiesner JB, Erion MD. Boyer SH, et al. Among authors: nagahisa a. J Med Chem. 2005 Oct 6;48(20):6430-41. doi: 10.1021/jm0503650. J Med Chem. 2005. PMID: 16190769

6

Tenidap, a structurally novel drug for the treatment of arthritis: antiinflammatory and analgesic properties.

Moore PF, Larson DL, Otterness IG, Weissman A, Kadin SB, Sweeney FJ, Eskra JD, Nagahisa A, Sakakibara M, Carty TJ. Moore PF, et al. Among authors: nagahisa a. Inflamm Res. 1996 Feb;45(2):54-61. doi: 10.1007/BF02265116. Inflamm Res. 1996. PMID: 8907585

7

Differential SAR of quinuclidine SP antagonists between rat and human-type receptors.

Snider RM, Longo KP, Zorn SH, Morrone J, Jackson ER, Nagahisa A, Kanai Y, Suga O, Nakagaki M, Drozda SE, et al. Snider RM, et al. Among authors: nagahisa a. Regul Pept. 1993 Jul 2;46(1-2):290-2. doi: 10.1016/0167-0115(93)90063-e. Regul Pept. 1993. PMID: 7692519 No abstract available.

8

Characterization of CP-122,721; a nonpeptide antagonist of the neurokinin NK1 receptor.

McLean S, Ganong A, Seymour PA, Bryce DK, Crawford RT, Morrone J, Reynolds LS, Schmidt AW, Zorn S, Watson J, Fossa A, DePasquale M, Rosen T, Nagahisa A, Tsuchiya M, Heym J. McLean S, et al. Among authors: nagahisa a. J Pharmacol Exp Ther. 1996 May;277(2):900-8. J Pharmacol Exp Ther. 1996. PMID: 8627572

9

Anti-emetic activity of the novel nonpeptide tachykinin NK1 receptor antagonist ezlopitant (CJ-11,974) against acute and delayed cisplatin-induced emesis in the ferret.

Tsuchiya M, Fujiwara Y, Kanai Y, Mizutani M, Shimada K, Suga O, Ueda S, Watson JW, Nagahisa A. Tsuchiya M, et al. Among authors: nagahisa a. Pharmacology. 2002 Nov;66(3):144-52. doi: 10.1159/000063796. Pharmacology. 2002. PMID: 12372904

10

The non-peptide tachykinin antagonist, CP-96,345, is a potent inhibitor of neurogenic inflammation.

Lembeck F, Donnerer J, Tsuchiya M, Nagahisa A. Lembeck F, et al. Among authors: nagahisa a. Br J Pharmacol. 1992 Mar;105(3):527-30. doi: 10.1111/j.1476-5381.1992.tb09013.x. Br J Pharmacol. 1992. PMID: 1378337 Free PMC article.

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