Alessi DR - Search Results

1

Crystal structure of the phosphatidylinositol 3,4-bisphosphate-binding pleckstrin homology (PH) domain of tandem PH-domain-containing protein 1 (TAPP1): molecular basis of lipid specificity.

Thomas CC, Dowler S, Deak M, Alessi DR, van Aalten DM. Thomas CC, et al. Among authors: alessi dr. Biochem J. 2001 Sep 1;358(Pt 2):287-94. doi: 10.1042/0264-6021:3580287. Biochem J. 2001. PMID: 11513726 Free PMC article.

2

The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated protein kinase pathway in L6 cells between Ras and Raf.

Cross DA, Alessi DR, Vandenheede JR, McDowell HE, Hundal HS, Cohen P. Cross DA, et al. Among authors: alessi dr. Biochem J. 1994 Oct 1;303 ( Pt 1)(Pt 1):21-6. doi: 10.1042/bj3030021. Biochem J. 1994. PMID: 7945242 Free PMC article.

3

Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activation.

James SR, Downes CP, Gigg R, Grove SJ, Holmes AB, Alessi DR. James SR, et al. Among authors: alessi dr. Biochem J. 1996 May 1;315 ( Pt 3)(Pt 3):709-13. doi: 10.1042/bj3150709. Biochem J. 1996. PMID: 8645147 Free PMC article.

4

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase.

Alessi DR, Deak M, Casamayor A, Caudwell FB, Morrice N, Norman DG, Gaffney P, Reese CB, MacDougall CN, Harbison D, Ashworth A, Bownes M. Alessi DR, et al. Curr Biol. 1997 Oct 1;7(10):776-89. doi: 10.1016/s0960-9822(06)00336-8. Curr Biol. 1997. PMID: 9368760 Free article.

5

Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha.

Walker KS, Deak M, Paterson A, Hudson K, Cohen P, Alessi DR. Walker KS, et al. Among authors: alessi dr. Biochem J. 1998 Apr 1;331 ( Pt 1)(Pt 1):299-308. doi: 10.1042/bj3310299. Biochem J. 1998. PMID: 9512493 Free PMC article.

6

Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB.

Deak M, Clifton AD, Lucocq LM, Alessi DR. Deak M, et al. Among authors: alessi dr. EMBO J. 1998 Aug 3;17(15):4426-41. doi: 10.1093/emboj/17.15.4426. EMBO J. 1998. PMID: 9687510 Free PMC article.

7

The activation of protein kinase B by H2O2 or heat shock is mediated by phosphoinositide 3-kinase and not by mitogen-activated protein kinase-activated protein kinase-2.

Shaw M, Cohen P, Alessi DR. Shaw M, et al. Among authors: alessi dr. Biochem J. 1998 Nov 15;336 ( Pt 1)(Pt 1):241-6. doi: 10.1042/bj3360241. Biochem J. 1998. PMID: 9806907 Free PMC article.

8

Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1.

Currie RA, Walker KS, Gray A, Deak M, Casamayor A, Downes CP, Cohen P, Alessi DR, Lucocq J. Currie RA, et al. Among authors: alessi dr. Biochem J. 1999 Feb 1;337 ( Pt 3)(Pt 3):575-83. Biochem J. 1999. PMID: 9895304 Free PMC article.

9

PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.

Balendran A, Casamayor A, Deak M, Paterson A, Gaffney P, Currie R, Downes CP, Alessi DR. Balendran A, et al. Among authors: alessi dr. Curr Biol. 1999 Apr 22;9(8):393-404. doi: 10.1016/s0960-9822(99)80186-9. Curr Biol. 1999. PMID: 10226025 Free article.

10

Characterisation of a plant 3-phosphoinositide-dependent protein kinase-1 homologue which contains a pleckstrin homology domain.

Deak M, Casamayor A, Currie RA, Downes CP, Alessi DR. Deak M, et al. Among authors: alessi dr. FEBS Lett. 1999 May 28;451(3):220-6. doi: 10.1016/s0014-5793(99)00556-6. FEBS Lett. 1999. PMID: 10371193 Free article.

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