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Molecular mechanism underlying the action of a novel fusion inhibitor of influenza A virus.
Luo G, Torri A, Harte WE, Danetz S, Cianci C, Tiley L, Day S, Mullaney D, Yu KL, Ouellet C, Dextraze P, Meanwell N, Colonno R, Krystal M. Luo G, et al. J Virol. 1997 May;71(5):4062-70. doi: 10.1128/JVI.71.5.4062-4070.1997. J Virol. 1997. PMID: 9094684 Free PMC article.
Recently, we identified and characterized BMY-27709 as an inhibitor of the H1 and H2 subtypes of influenza A virus that specifically inhibits the HA function necessary for virus-cell membrane fusion (G.-X. Luo, R. Colonno, and M. Krystal, Virology 226:66-76, 1996). …
Recently, we identified and characterized BMY-27709 as an inhibitor of the H1 and H2 subtypes of influenza A virus that specifically inhibit …
pH-dependent changes in photoaffinity labeling patterns of the H1 influenza virus hemagglutinin by using an inhibitor of viral fusion.
Cianci C, Yu KL, Dischino DD, Harte W, Deshpande M, Luo G, Colonno RJ, Meanwell NA, Krystal M. Cianci C, et al. Among authors: luo g. J Virol. 1999 Mar;73(3):1785-94. doi: 10.1128/JVI.73.3.1785-1794.1999. J Virol. 1999. PMID: 9971755 Free PMC article.
A class of compounds that specifically interact with the HA protein of H1 and H2 subtype viruses and inhibit this conformational change was recently described (G. X. Luo et al., Virology 226:66-76, 1996, and J. Virol. 71:4062-4070, 1997). In this study, purified HA …
A class of compounds that specifically interact with the HA protein of H1 and H2 subtype viruses and inhibit this conformational change was …
Novel quinolizidine salicylamide influenza fusion inhibitors.
Yu KL, Ruediger E, Luo G, Cianci C, Danetz S, Tiley L, Trehan AK, Monkovic I, Pearce B, Martel A, Krystal M, Meanwell NA. Yu KL, et al. Among authors: luo g. Bioorg Med Chem Lett. 1999 Aug 2;9(15):2177-80. doi: 10.1016/s0960-894x(99)00361-3. Bioorg Med Chem Lett. 1999. PMID: 10465540
Salicylamide inhibitors of influenza virus fusion.
Combrink KD, Gulgeze HB, Yu KL, Pearce BC, Trehan AK, Wei J, Deshpande M, Krystal M, Torri A, Luo G, Cianci C, Danetz S, Tiley L, Meanwell NA. Combrink KD, et al. Among authors: luo g. Bioorg Med Chem Lett. 2000 Aug 7;10(15):1649-52. doi: 10.1016/s0960-894x(00)00335-8. Bioorg Med Chem Lett. 2000. PMID: 10937716
Orally active fusion inhibitor of respiratory syncytial virus.
Cianci C, Yu KL, Combrink K, Sin N, Pearce B, Wang A, Civiello R, Voss S, Luo G, Kadow K, Genovesi EV, Venables B, Gulgeze H, Trehan A, James J, Lamb L, Medina I, Roach J, Yang Z, Zadjura L, Colonno R, Clark J, Meanwell N, Krystal M. Cianci C, et al. Among authors: luo g. Antimicrob Agents Chemother. 2004 Feb;48(2):413-22. doi: 10.1128/AAC.48.2.413-422.2004. Antimicrob Agents Chemother. 2004. PMID: 14742189 Free PMC article.
4,985 results