Lerner RA - Search Results

1

Antibody catalysis of the oxidation of water.

Wentworth P Jr, Jones LH, Wentworth AD, Zhu X, Larsen NA, Wilson IA, Xu X, Goddard WA 3rd, Janda KD, Eschenmoser A, Lerner RA. Wentworth P Jr, et al. Among authors: lerner ra. Science. 2001 Sep 7;293(5536):1806-11. doi: 10.1126/science.1062722. Science. 2001. PMID: 11546867

2

Evidence for the production of trioxygen species during antibody-catalyzed chemical modification of antigens.

Wentworth P Jr, Wentworth AD, Zhu X, Wilson IA, Janda KD, Eschenmoser A, Lerner RA. Wentworth P Jr, et al. Among authors: lerner ra. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1490-3. doi: 10.1073/pnas.0437831100. Epub 2003 Feb 7. Proc Natl Acad Sci U S A. 2003. PMID: 12576548 Free PMC article.

3

Probing the antibody-catalyzed water-oxidation pathway at atomic resolution.

Zhu X, Wentworth P Jr, Wentworth AD, Eschenmoser A, Lerner RA, Wilson IA. Zhu X, et al. Among authors: lerner ra. Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2247-52. doi: 10.1073/pnas.0307311101. Proc Natl Acad Sci U S A. 2004. PMID: 14982995 Free PMC article.

4

Immunoglobulins can utilize riboflavin (Vitamin B2) to activate the antibody-catalyzed water oxidation pathway.

Nieva J, Kerwin L, Wentworth AD, Lerner RA, Wentworth P Jr. Nieva J, et al. Among authors: lerner ra. Immunol Lett. 2006 Feb 28;103(1):33-8. doi: 10.1016/j.imlet.2005.11.020. Epub 2005 Dec 15. Immunol Lett. 2006. PMID: 16386801

5

Deeply inverted electron-hole recombination in a luminescent antibody-stilbene complex.

Debler EW, Kaufmann GF, Meijler MM, Heine A, Mee JM, Pljevaljcic G, Di Bilio AJ, Schultz PG, Millar DP, Janda KD, Wilson IA, Gray HB, Lerner RA. Debler EW, et al. Among authors: lerner ra. Science. 2008 Feb 29;319(5867):1232-5. doi: 10.1126/science.1153445. Science. 2008. PMID: 18309081 Free article.

6

Evidence for antibody-catalyzed ozone formation in bacterial killing and inflammation.

Wentworth P Jr, McDunn JE, Wentworth AD, Takeuchi C, Nieva J, Jones T, Bautista C, Ruedi JM, Gutierrez A, Janda KD, Babior BM, Eschenmoser A, Lerner RA. Wentworth P Jr, et al. Among authors: lerner ra. Science. 2002 Dec 13;298(5601):2195-9. doi: 10.1126/science.1077642. Epub 2002 Nov 14. Science. 2002. PMID: 12434011

7

An unexpectedly efficient catalytic antibody operating by ping-pong and induced fit mechanisms.

Wirsching P, Ashley JA, Benkovic SJ, Janda KD, Lerner RA. Wirsching P, et al. Among authors: lerner ra. Science. 1991 May 3;252(5006):680-5. doi: 10.1126/science.2024120. Science. 1991. PMID: 2024120

8

The enzymic nature of antibody catalysis: development of multistep kinetic processing.

Benkovic SJ, Adams JA, Borders CL Jr, Janda KD, Lerner RA. Benkovic SJ, et al. Among authors: lerner ra. Science. 1990 Nov 23;250(4984):1135-9. doi: 10.1126/science.2251500. Science. 1990. PMID: 2251500

9

Antibody catalyzed cationic cyclization.

Li T, Janda KD, Ashley JA, Lerner RA. Li T, et al. Among authors: lerner ra. Science. 1994 May 27;264(5163):1289-93. doi: 10.1126/science.8191282. Science. 1994. PMID: 8191282

10

Control of the exo and endo pathways of the Diels-Alder reaction by antibody catalysis.

Gouverneur VE, Houk KN, de Pascual-Teresa B, Beno B, Janda KD, Lerner RA. Gouverneur VE, et al. Among authors: lerner ra. Science. 1993 Oct 8;262(5131):204-8. doi: 10.1126/science.8211138. Science. 1993. PMID: 8211138

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