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Hypertensive end-organ damage and premature mortality are p38 mitogen-activated protein kinase-dependent in a rat model of cardiac hypertrophy and dysfunction.
Behr TM, Nerurkar SS, Nelson AH, Coatney RW, Woods TN, Sulpizio A, Chandra S, Brooks DP, Kumar S, Lee JC, Ohlstein EH, Angermann CE, Adams JL, Sisko J, Sackner-Bernstein JD, Willette RN. Behr TM, et al. Among authors: adams jl. Circulation. 2001 Sep 11;104(11):1292-8. doi: 10.1161/hc3601.094275. Circulation. 2001. PMID: 11551882
SB 239063, a second-generation p38 mitogen-activated protein kinase inhibitor, reduces brain injury and neurological deficits in cerebral focal ischemia.
Barone FC, Irving EA, Ray AM, Lee JC, Kassis S, Kumar S, Badger AM, White RF, McVey MJ, Legos JJ, Erhardt JA, Nelson AH, Ohlstein EH, Hunter AJ, Ward K, Smith BR, Adams JL, Parsons AA. Barone FC, et al. Among authors: adams jl. J Pharmacol Exp Ther. 2001 Feb;296(2):312-21. J Pharmacol Exp Ther. 2001. PMID: 11160612
Inhibition of p38 mitogen-activated protein kinase provides neuroprotection in cerebral focal ischemia.
Barone FC, Irving EA, Ray AM, Lee JC, Kassis S, Kumar S, Badger AM, Legos JJ, Erhardt JA, Ohlstein EH, Hunter AJ, Harrison DC, Philpott K, Smith BR, Adams JL, Parsons AA. Barone FC, et al. Among authors: adams jl. Med Res Rev. 2001 Mar;21(2):129-45. doi: 10.1002/1098-1128(200103)21:2<129::aid-med1003>3.0.co;2-h. Med Res Rev. 2001. PMID: 11223862 Review.
Inhibition of p38 MAP kinase as a therapeutic strategy.
Lee JC, Kumar S, Griswold DE, Underwood DC, Votta BJ, Adams JL. Lee JC, et al. Among authors: adams jl. Immunopharmacology. 2000 May;47(2-3):185-201. doi: 10.1016/s0162-3109(00)00206-x. Immunopharmacology. 2000. PMID: 10878289 Review.
Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis.
Badger AM, Griswold DE, Kapadia R, Blake S, Swift BA, Hoffman SJ, Stroup GB, Webb E, Rieman DJ, Gowen M, Boehm JC, Adams JL, Lee JC. Badger AM, et al. Among authors: adams jl. Arthritis Rheum. 2000 Jan;43(1):175-83. doi: 10.1002/1529-0131(200001)43:1<175::AID-ANR22>3.0.CO;2-S. Arthritis Rheum. 2000. PMID: 10643714 Free article.
352 results