Dorso CR - Search Results

1

Arylcyclopropanecarboxyl guanidines as novel, potent, and selective inhibitors of the sodium hydrogen exchanger isoform-1.

Ahmad S, Doweyko LM, Dugar S, Grazier N, Ngu K, Wu SC, Yost KJ, Chen BC, Gougoutas JZ, DiMarco JD, Lan SJ, Gavin BJ, Chen AY, Dorso CR, Serafino R, Kirby M, Atwal KS. Ahmad S, et al. Among authors: dorso cr. J Med Chem. 2001 Sep 27;44(20):3302-10. doi: 10.1021/jm010100v. J Med Chem. 2001. PMID: 11563929

2

Aminoimidazoles as bioisosteres of acylguanidines: novel, potent, selective and orally bioavailable inhibitors of the sodium hydrogen exchanger isoform-1.

Ahmad S, Ngu K, Combs DW, Wu SC, Weinstein DS, Liu W, Chen BC, Chandrasena G, Dorso CR, Kirby M, Atwal KS. Ahmad S, et al. Among authors: dorso cr. Bioorg Med Chem Lett. 2004 Jan 5;14(1):177-80. doi: 10.1016/j.bmcl.2003.09.066. Bioorg Med Chem Lett. 2004. PMID: 14684323

3

Synthesis and biological activity of 5-aryl-4-(4-(5-methyl-1H-imidazol-4-yl)piperidin-1-yl)pyrimidine analogs as potent, highly selective, and orally bioavailable NHE-1 inhibitors.

Atwal KS, O'Neil SV, Ahmad S, Doweyko L, Kirby M, Dorso CR, Chandrasena G, Chen BC, Zhao R, Zahler R. Atwal KS, et al. Among authors: dorso cr. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4796-9. doi: 10.1016/j.bmcl.2006.06.077. Epub 2006 Jul 25. Bioorg Med Chem Lett. 2006. PMID: 16870436

4

The effects of novel cathepsin E inhibitors on the big endothelin pressor response in conscious rats.

Bird JE, Waldron TL, Little DK, Asaad MM, Dorso CR, DiDonato G, Norman JA. Bird JE, et al. Among authors: dorso cr. Biochem Biophys Res Commun. 1992 Jan 15;182(1):224-31. doi: 10.1016/s0006-291x(05)80134-2. Biochem Biophys Res Commun. 1992. PMID: 1731782

5

In vivo pharmacology of dual neutral endopeptidase/angiotensin-converting enzyme inhibitors.

Seymour AA, Asaad MM, Abboa-Offei BE, Smith PL, Rogers WL, Dorso CR. Seymour AA, et al. Among authors: dorso cr. J Cardiovasc Pharmacol. 1996 Nov;28(5):672-8. doi: 10.1097/00005344-199611000-00010. J Cardiovasc Pharmacol. 1996. PMID: 8945681

6

A role for endothelin ETA receptors in regulation of renal function in spontaneously hypertensive rats.

Bird JE, Webb ML, Giancarli MR, Chao C, Dorso CR, Asaad MM. Bird JE, et al. Among authors: dorso cr. Eur J Pharmacol. 1995 Dec 27;294(1):183-9. doi: 10.1016/0014-2999(95)00537-4. Eur J Pharmacol. 1995. PMID: 8788430

7

Potency, selectivity and prolonged binding of saxagliptin to DPP4: maintenance of DPP4 inhibition by saxagliptin in vitro and ex vivo when compared to a rapidly-dissociating DPP4 inhibitor.

Wang A, Dorso C, Kopcho L, Locke G, Langish R, Harstad E, Shipkova P, Marcinkeviciene J, Hamann L, Kirby MS. Wang A, et al. BMC Pharmacol. 2012 Apr 4;12:2. doi: 10.1186/1471-2210-12-2. BMC Pharmacol. 2012. PMID: 22475049 Free PMC article.

8

Determinants of in vivo activity of neutral endopeptidase 3.4.24.11 and angiotensin converting enzyme inhibitors.

Seymour AA, Asaad MM, Abboa-Offei BE, Smith PL, Rogers WL, Dorso CR. Seymour AA, et al. Among authors: dorso cr. J Pharmacol Exp Ther. 1996 Feb;276(2):708-13. J Pharmacol Exp Ther. 1996. PMID: 8632340

9

Renal and depressor activities of inhibitors of neutral endopeptidase and angiotensin converting enzyme in monkeys infused with angiotensin II.

Seymour AA, Asaad MM, Abboa-Offei BE, Smith PL, Mathers PD, Rogers WL, Dorso CR. Seymour AA, et al. Among authors: dorso cr. J Cardiovasc Pharmacol. 1996 Nov;28(5):651-8. doi: 10.1097/00005344-199611000-00007. J Cardiovasc Pharmacol. 1996. PMID: 8945678

10

Combined inhibition of neutral endopeptidase and angiotensin converting enzyme in cardiomyopathic hamsters with compensated heart failure.

Trippodo NC, Fox M, Natarajan V, Panchal BC, Dorso CR, Asaad MM. Trippodo NC, et al. Among authors: dorso cr. J Pharmacol Exp Ther. 1993 Oct;267(1):108-16. J Pharmacol Exp Ther. 1993. PMID: 8229737

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