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A novel long chain polyunsaturated fatty acid, beta-Oxa 21:3n-3, inhibits T lymphocyte proliferation, cytokine production, delayed-type hypersensitivity, and carrageenan-induced paw reaction and selectively targets intracellular signals.
Costabile M, Hii CS, Robinson BS, Rathjen DA, Pitt M, Easton C, Miller RC, Poulos A, Murray AW, Ferrante A. Costabile M, et al. Among authors: poulos a. J Immunol. 2001 Oct 1;167(7):3980-7. doi: 10.4049/jimmunol.167.7.3980. J Immunol. 2001. PMID: 11564817
A novel beta-oxa polyunsaturated fatty acid downregulates the activation of the IkappaB kinase/nuclear factor kappaB pathway, inhibits expression of endothelial cell adhesion molecules, and depresses inflammation.
Ferrante A, Robinson BS, Singh H, Jersmann HP, Ferrante JV, Huang ZH, Trout NA, Pitt MJ, Rathjen DA, Easton CJ, Poulos A, Prager RH, Lee FS, Hii CS. Ferrante A, et al. Among authors: poulos a. Circ Res. 2006 Jul 7;99(1):34-41. doi: 10.1161/01.RES.0000231292.66084.cd. Epub 2006 Jun 8. Circ Res. 2006. PMID: 16763165
Polyenoic very-long-chain fatty acids mobilize intracellular calcium from a thapsigargin-insensitive pool in human neutrophils. The relationship between Ca2+ mobilization and superoxide production induced by long- and very-long-chain fatty acids.
Hardy SJ, Robinson BS, Ferrante A, Hii CS, Johnson DW, Poulos A, Murray AW. Hardy SJ, et al. Among authors: poulos a. Biochem J. 1995 Oct 15;311 ( Pt 2)(Pt 2):689-97. doi: 10.1042/bj3110689. Biochem J. 1995. PMID: 7487914 Free PMC article.
295 results