Smyth JF - Search Results

1

High-performance liquid chromatographic technique for the simultaneous determination of lactone and hydroxy acid forms of camptothecin and SN-38 in tissue culture media and cancer cells.

Boyd G, Smyth JF, Jodrell DI, Cummings J. Boyd G, et al. Among authors: smyth jf. Anal Biochem. 2001 Oct 1;297(1):15-24. doi: 10.1006/abio.2001.5317. Anal Biochem. 2001. PMID: 11567523

2

Factors influencing the cellular accumulation of SN-38 and camptothecin.

Cummings J, Boyd G, Macpherson JS, Wolf H, Smith G, Smyth JF, Jodrell DI. Cummings J, et al. Among authors: smyth jf. Cancer Chemother Pharmacol. 2002 Mar;49(3):194-200. doi: 10.1007/s00280-001-0393-3. Epub 2002 Jan 22. Cancer Chemother Pharmacol. 2002. PMID: 11935211

3

Enhanced clearance of topoisomerase I inhibitors from human colon cancer cells by glucuronidation.

Cummings J, Boyd G, Ethell BT, Macpherson JS, Burchell B, Smyth JF, Jodrell DI. Cummings J, et al. Among authors: smyth jf. Biochem Pharmacol. 2002 Feb 15;63(4):607-13. doi: 10.1016/s0006-2952(01)00812-7. Biochem Pharmacol. 2002. PMID: 11992628

4

Determination of the novel topoisomerase I inhibitor NU/ICRF 505 and its major metabolite in plasma, tissue and tumour by high-performance liquid chromatography.

Cummings J, Meikle I, Macpherson JS, Smyth JF. Cummings J, et al. Among authors: smyth jf. J Chromatogr B Biomed Appl. 1996 Oct 11;685(1):159-64. doi: 10.1016/0378-4347(96)00155-7. J Chromatogr B Biomed Appl. 1996. PMID: 8930764

5

Determination of covalent binding to intact DNA, RNA, and oligonucleotides by intercalating anticancer drugs using high-performance liquid chromatography. Studies with doxorubicin and NADPH cytochrome P-450 reductase.

Cummings J, Bartoszek A, Smyth JF. Cummings J, et al. Among authors: smyth jf. Anal Biochem. 1991 Apr;194(1):146-55. doi: 10.1016/0003-2697(91)90162-m. Anal Biochem. 1991. PMID: 1714250

6

Determination of reactive nitrogen mustard anticancer drugs in plasma by high-performance liquid chromatography using derivatization.

Cummings J, MacLellan A, Smyth JF, Farmer PB. Cummings J, et al. Among authors: smyth jf. Anal Chem. 1991 Aug 1;63(15):1514-9. doi: 10.1021/ac00015a004. Anal Chem. 1991. PMID: 1952082

7

Method for the determination of gamma-L-glutamyl-L-dihydroxyphenylalanine and its major metabolites L-dihydroxyphenylalanine, dopamine and 3,4-dihydroxyphenylacetic acid by high-performance liquid chromatography with electrochemical detection.

Cummings J, Matheson LM, Smyth JF. Cummings J, et al. Among authors: smyth jf. J Chromatogr. 1990 Jun 8;528(1):43-53. doi: 10.1016/s0378-4347(00)82361-0. J Chromatogr. 1990. PMID: 2117019

8

Application of high-performance liquid chromatography for recognition of covalent nucleic acid modification with anticancer drugs.

Cummings J, French RC, Smyth JF. Cummings J, et al. Among authors: smyth jf. J Chromatogr. 1993 Aug 25;618(1-2):251-76. doi: 10.1016/0378-4347(93)80037-5. J Chromatogr. 1993. PMID: 8227259 Review.

9

Antisense Bcl-xl down-regulation switches the response to topoisomerase I inhibition from senescence to apoptosis in colorectal cancer cells, enhancing global cytotoxicity.

Hayward RL, Macpherson JS, Cummings J, Monia BP, Smyth JF, Jodrell DI. Hayward RL, et al. Among authors: smyth jf. Clin Cancer Res. 2003 Jul;9(7):2856-65. Clin Cancer Res. 2003. PMID: 12855666

10

Glucuronidation as a mechanism of intrinsic drug resistance in colon cancer cells: contribution of drug transport proteins.

Cummings J, Zelcer N, Allen JD, Yao D, Boyd G, Maliepaard M, Friedberg TH, Smyth JF, Jodrell DI. Cummings J, et al. Among authors: smyth jf. Biochem Pharmacol. 2004 Jan 1;67(1):31-9. doi: 10.1016/j.bcp.2003.07.019. Biochem Pharmacol. 2004. PMID: 14667926

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