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Niemann-pick type C2 deficiency in human fibroblasts confers robust and selective activation of prostaglandin E2 biosynthesis.
Frolov A, Dong H, Jiang M, Yang L, Cook EC, Matnani R, Hammock BD, Crofford LJ. Frolov A, et al. J Biol Chem. 2013 Aug 16;288(33):23696-703. doi: 10.1074/jbc.M112.445916. Epub 2013 Jun 27. J Biol Chem. 2013. PMID: 23814065 Free PMC article.
J., and Frolov, A. (2011) J. Biol. Chem. 286, 2078-2087). Here we report that NPC2-deficiency leads to a dramatic up-regulation of the arachidonic acid (AA) metabolic pathway in human fibroblasts. ...The specific phenotypic changes resulted in a >10 …
J., and Frolov, A. (2011) J. Biol. Chem. 286, 2078-2087). Here we report that NPC2-deficiency leads to a dramatic up-re …
845 results