Langguth P - Search Results

1

Intestinal drug efflux: formulation and food effects.

Wagner D, Spahn-Langguth H, Hanafy A, Koggel A, Langguth P. Wagner D, et al. Among authors: langguth p. Adv Drug Deliv Rev. 2001 Oct 1;50 Suppl 1:S13-31. doi: 10.1016/s0169-409x(01)00183-1. Adv Drug Deliv Rev. 2001. PMID: 11576693 Review.

2

Enantiospecific high-performance liquid chromatographic assay with fluorescence detection for the monoamine oxidase inhibitor tranylcypromine and its applicability in pharmacokinetic studies.

Spahn-Langguth H, Hahn G, Mutschler E, Möhrke W, Langguth P. Spahn-Langguth H, et al. Among authors: langguth p. J Chromatogr. 1992 Dec 23;584(2):229-37. doi: 10.1016/0378-4347(92)80580-j. J Chromatogr. 1992. PMID: 1484108

3

Variable gastric emptying and discontinuities in drug absorption profiles: dependence of rates and extent of cimetidine absorption on motility phase and pH.

Langguth P, Lee KM, Spahn-Langguth H, Amidon GL. Langguth P, et al. Biopharm Drug Dispos. 1994 Dec;15(9):719-46. doi: 10.1002/bdd.2510150902. Biopharm Drug Dispos. 1994. PMID: 7888602

4

Evidence for intestinal secretion as an additional clearance pathway of talinolol enantiomers: concentration- and dose-dependent absorption in vitro and in vivo.

Wetterich U, Spahn-Langguth H, Mutschler E, Terhaag B, Rösch W, Langguth P. Wetterich U, et al. Among authors: langguth p. Pharm Res. 1996 Apr;13(4):514-22. doi: 10.1023/a:1016029601311. Pharm Res. 1996. PMID: 8710739 Clinical Trial.

5

Celiprolol double-peak occurrence and gastric motility: nonlinear mixed effects modeling of bioavailability data obtained in dogs.

Lipka E, Lee ID, Langguth P, Spahn-Langguth H, Mutschler E, Amidon GL. Lipka E, et al. Among authors: langguth p. J Pharmacokinet Biopharm. 1995 Jun;23(3):267-86. doi: 10.1007/BF02354285. J Pharmacokinet Biopharm. 1995. PMID: 8834196 Free article.

6

P-glycoprotein transporters and the gastrointestinal tract: evaluation of the potential in vivo relevance of in vitro data employing talinolol as model compound.

Spahn-Langguth H, Baktir G, Radschuweit A, Okyar A, Terhaag B, Ader P, Hanafy A, Langguth P. Spahn-Langguth H, et al. Among authors: langguth p. Int J Clin Pharmacol Ther. 1998 Jan;36(1):16-24. Int J Clin Pharmacol Ther. 1998. PMID: 9476144

7

P-Glycoprotein (P-gp) mediated efflux in Caco-2 cell monolayers: the influence of culturing conditions and drug exposure on P-gp expression levels.

Anderle P, Niederer E, Rubas W, Hilgendorf C, Spahn-Langguth H, Wunderli-Allenspach H, Merkle HP, Langguth P. Anderle P, et al. Among authors: langguth p. J Pharm Sci. 1998 Jun;87(6):757-62. doi: 10.1021/js970372e. J Pharm Sci. 1998. PMID: 9607955

8

Radioligand-binding assay employing P-glycoprotein-overexpressing cells: testing drug affinities to the secretory intestinal multidrug transporter.

Döppenschmitt S, Spahn-Langguth H, Regårdh CG, Langguth P. Döppenschmitt S, et al. Among authors: langguth p. Pharm Res. 1998 Jul;15(7):1001-6. doi: 10.1023/a:1011965707998. Pharm Res. 1998. PMID: 9688051

9

Characterization of binding properties to human P-glycoprotein: development of a [3H]verapamil radioligand-binding assay.

Döppenschmitt S, Langguth P, Regårdh CG, Andersson TB, Hilgendorf C, Spahn-Langguth H. Döppenschmitt S, et al. Among authors: langguth p. J Pharmacol Exp Ther. 1999 Jan;288(1):348-57. J Pharmacol Exp Ther. 1999. PMID: 9862789

10

Role of P-glycoprotein-mediated secretion in absorptive drug permeability: An approach using passive membrane permeability and affinity to P-glycoprotein.

Döppenschmitt S, Spahn-Langguth H, Regårdh CG, Langguth P. Döppenschmitt S, et al. Among authors: langguth p. J Pharm Sci. 1999 Oct;88(10):1067-72. doi: 10.1021/js980378j. J Pharm Sci. 1999. PMID: 10514357

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