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Safety assessment, in vitro and in vivo, and pharmacokinetics of emivirine, a potent and selective nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1.
Szczech GM, Furman P, Painter GR, Barry DW, Borroto-Esoda K, Grizzle TB, Blum MR, Sommadossi J, Endoh R, Niwa T, Yamamoto M, Moxham C. Szczech GM, et al. Antimicrob Agents Chemother. 2000 Jan;44(1):123-30. doi: 10.1128/AAC.44.1.123-130.2000. Antimicrob Agents Chemother. 2000. PMID: 10602732 Free PMC article.
Mechanism of action of 1-beta-D-2,6-diaminopurine dioxolane, a prodrug of the human immunodeficiency virus type 1 inhibitor 1-beta-D-dioxolane guanosine.
Furman PA, Jeffrey J, Kiefer LL, Feng JY, Anderson KS, Borroto-Esoda K, Hill E, Copeland WC, Chu CK, Sommadossi JP, Liberman I, Schinazi RF, Painter GR. Furman PA, et al. Among authors: sommadossi jp. Antimicrob Agents Chemother. 2001 Jan;45(1):158-65. doi: 10.1128/AAC.45.1.158-165.2001. Antimicrob Agents Chemother. 2001. PMID: 11120959 Free PMC article.
Antiviral L-nucleosides specific for hepatitis B virus infection.
Bryant ML, Bridges EG, Placidi L, Faraj A, Loi AG, Pierra C, Dukhan D, Gosselin G, Imbach JL, Hernandez B, Juodawlkis A, Tennant B, Korba B, Cote P, Marion P, Cretton-Scott E, Schinazi RF, Sommadossi JP. Bryant ML, et al. Among authors: sommadossi jp. Antimicrob Agents Chemother. 2001 Jan;45(1):229-35. doi: 10.1128/AAC.45.1.229-235.2001. Antimicrob Agents Chemother. 2001. PMID: 11120971 Free PMC article.
Selective inhibition of human immunodeficiency viruses by racemates and enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine.
Schinazi RF, McMillan A, Cannon D, Mathis R, Lloyd RM, Peck A, Sommadossi JP, St Clair M, Wilson J, Furman PA, et al. Schinazi RF, et al. Among authors: sommadossi jp. Antimicrob Agents Chemother. 1992 Nov;36(11):2423-31. doi: 10.1128/AAC.36.11.2423. Antimicrob Agents Chemother. 1992. PMID: 1283296 Free PMC article.
Stable concentrations of zidovudine, stavudine, lamivudine, abacavir, and nevirapine in serum and cerebrospinal fluid during 2 years of therapy.
van Praag RM, van Weert EC, van Heeswijk RP, Zhou XJ, Sommadossi JP, Jurriaans S, Lange JM, Hoetelmans RM, Prins JM. van Praag RM, et al. Among authors: sommadossi jp. Antimicrob Agents Chemother. 2002 Mar;46(3):896-9. doi: 10.1128/AAC.46.3.896-899.2002. Antimicrob Agents Chemother. 2002. PMID: 11850283 Free PMC article. Clinical Trial.
AT-527, a Double Prodrug of a Guanosine Nucleotide Analog, Is a Potent Inhibitor of SARS-CoV-2 In Vitro and a Promising Oral Antiviral for Treatment of COVID-19.
Good SS, Westover J, Jung KH, Zhou XJ, Moussa A, La Colla P, Collu G, Canard B, Sommadossi JP. Good SS, et al. Among authors: sommadossi jp. Antimicrob Agents Chemother. 2021 Mar 18;65(4):e02479-20. doi: 10.1128/AAC.02479-20. Print 2021 Mar 18. Antimicrob Agents Chemother. 2021. PMID: 33558299 Free PMC article.
Population pharmacokinetics of nevirapine, zidovudine, and didanosine in human immunodeficiency virus-infected patients. The National Institute of Allergy and Infectious Diseases AIDS Clinical Trials Group Protocol 241 Investigators.
Zhou XJ, Sheiner LB, D'Aquila RT, Hughes MD, Hirsch MS, Fischl MA, Johnson VA, Myers M, Sommadossi JP. Zhou XJ, et al. Among authors: sommadossi jp. Antimicrob Agents Chemother. 1999 Jan;43(1):121-8. doi: 10.1128/AAC.43.1.121. Antimicrob Agents Chemother. 1999. PMID: 9869576 Free PMC article. Clinical Trial.
Pharmacokinetics of beta-L-2',3'-dideoxy-5-fluorocytidine in rhesus monkeys.
Martin LT, Cretton-Scott E, Schinazi RF, Zhou XJ, McClure HM, Mathe C, Gosselin G, Imbach JL, Sommadossi JP. Martin LT, et al. Among authors: sommadossi jp. Antimicrob Agents Chemother. 1999 Apr;43(4):920-4. doi: 10.1128/AAC.43.4.920. Antimicrob Agents Chemother. 1999. PMID: 10103200 Free PMC article.
170 results