Tolbert WD - Search Results

1

The structural basis for substrate specificity and inhibition of human S-adenosylmethionine decarboxylase.

Tolbert WD, Ekstrom JL, Mathews II, Secrist JA 3rd, Kapoor P, Pegg AE, Ealick SE. Tolbert WD, et al. Biochemistry. 2001 Aug 14;40(32):9484-94. doi: 10.1021/bi010735w. Biochemistry. 2001. PMID: 11583147

2

Mechanism of human S-adenosylmethionine decarboxylase proenzyme processing as revealed by the structure of the S68A mutant.

Tolbert WD, Zhang Y, Cottet SE, Bennett EM, Ekstrom JL, Pegg AE, Ealick SE. Tolbert WD, et al. Biochemistry. 2003 Mar 4;42(8):2386-95. doi: 10.1021/bi0268854. Biochemistry. 2003. PMID: 12600205

3

Structure of a human S-adenosylmethionine decarboxylase self-processing ester intermediate and mechanism of putrescine stimulation of processing as revealed by the H243A mutant.

Ekstrom JL, Tolbert WD, Xiong H, Pegg AE, Ealick SE. Ekstrom JL, et al. Among authors: tolbert wd. Biochemistry. 2001 Aug 14;40(32):9495-504. doi: 10.1021/bi010736o. Biochemistry. 2001. PMID: 11583148

4

Pyruvoyl-dependent arginine decarboxylase from Methanococcus jannaschii: crystal structures of the self-cleaved and S53A proenzyme forms.

Tolbert WD, Graham DE, White RH, Ealick SE. Tolbert WD, et al. Structure. 2003 Mar;11(3):285-94. doi: 10.1016/s0969-2126(03)00026-1. Structure. 2003. PMID: 12623016 Free article.

5

Structure of neurolysin reveals a deep channel that limits substrate access.

Brown CK, Madauss K, Lian W, Beck MR, Tolbert WD, Rodgers DW. Brown CK, et al. Among authors: tolbert wd. Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3127-32. doi: 10.1073/pnas.051633198. Epub 2001 Mar 6. Proc Natl Acad Sci U S A. 2001. PMID: 11248043 Free PMC article.

6

3-Deoxy-D-manno-octulosonate-8-phosphate synthase from Escherichia coli. Model of binding of phosphoenolpyruvate and D-arabinose-5-phosphate.

Wagner T, Kretsinger RH, Bauerle R, Tolbert WD. Wagner T, et al. Among authors: tolbert wd. J Mol Biol. 2000 Aug 11;301(2):233-8. doi: 10.1006/jmbi.2000.3956. J Mol Biol. 2000. PMID: 10926505

7

Structural basis for agonism and antagonism of hepatocyte growth factor.

Tolbert WD, Daugherty-Holtrop J, Gherardi E, Vande Woude G, Xu HE. Tolbert WD, et al. Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13264-9. doi: 10.1073/pnas.1005183107. Epub 2010 Jul 12. Proc Natl Acad Sci U S A. 2010. PMID: 20624990 Free PMC article.

8

A mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonist.

Tolbert WD, Daugherty J, Gao C, Xie Q, Miranti C, Gherardi E, Vande Woude G, Xu HE. Tolbert WD, et al. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14592-7. doi: 10.1073/pnas.0704290104. Epub 2007 Sep 5. Proc Natl Acad Sci U S A. 2007. PMID: 17804794 Free PMC article.

9

Paring Down HIV Env: Design and Crystal Structure of a Stabilized Inner Domain of HIV-1 gp120 Displaying a Major ADCC Target of the A32 Region.

Tolbert WD, Gohain N, Veillette M, Chapleau JP, Orlandi C, Visciano ML, Ebadi M, DeVico AL, Fouts TR, Finzi A, Lewis GK, Pazgier M. Tolbert WD, et al. Structure. 2016 May 3;24(5):697-709. doi: 10.1016/j.str.2016.03.005. Epub 2016 Mar 31. Structure. 2016. PMID: 27041594 Free PMC article.

10

Co-receptor Binding Site Antibodies Enable CD4-Mimetics to Expose Conserved Anti-cluster A ADCC Epitopes on HIV-1 Envelope Glycoproteins.

Richard J, Pacheco B, Gohain N, Veillette M, Ding S, Alsahafi N, Tolbert WD, Prévost J, Chapleau JP, Coutu M, Jia M, Brassard N, Park J, Courter JR, Melillo B, Martin L, Tremblay C, Hahn BH, Kaufmann DE, Wu X, Smith AB 3rd, Sodroski J, Pazgier M, Finzi A. Richard J, et al. Among authors: tolbert wd. EBioMedicine. 2016 Oct;12:208-218. doi: 10.1016/j.ebiom.2016.09.004. Epub 2016 Sep 9. EBioMedicine. 2016. PMID: 27633463 Free PMC article.

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