Brennan ML - Search Results

1

Neutrophils employ the myeloperoxidase system to generate antimicrobial brominating and chlorinating oxidants during sepsis.

Gaut JP, Yeh GC, Tran HD, Byun J, Henderson JP, Richter GM, Brennan ML, Lusis AJ, Belaaouaj A, Hotchkiss RS, Heinecke JW. Gaut JP, et al. Among authors: brennan ml. Proc Natl Acad Sci U S A. 2001 Oct 9;98(21):11961-6. doi: 10.1073/pnas.211190298. Epub 2001 Oct 2. Proc Natl Acad Sci U S A. 2001. PMID: 11593004 Free PMC article.

2

Increased atherosclerosis in myeloperoxidase-deficient mice.

Brennan ML, Anderson MM, Shih DM, Qu XD, Wang X, Mehta AC, Lim LL, Shi W, Hazen SL, Jacob JS, Crowley JR, Heinecke JW, Lusis AJ. Brennan ML, et al. J Clin Invest. 2001 Feb;107(4):419-30. doi: 10.1172/JCI8797. J Clin Invest. 2001. PMID: 11181641 Free PMC article.

3

Mice lacking myeloperoxidase are more susceptible to experimental autoimmune encephalomyelitis.

Brennan M, Gaur A, Pahuja A, Lusis AJ, Reynolds WF. Brennan M, et al. J Neuroimmunol. 2001 Jan 1;112(1-2):97-105. doi: 10.1016/s0165-5728(00)00392-1. J Neuroimmunol. 2001. PMID: 11108938

4

Endothelial transcytosis of myeloperoxidase confers specificity to vascular ECM proteins as targets of tyrosine nitration.

Baldus S, Eiserich JP, Mani A, Castro L, Figueroa M, Chumley P, Ma W, Tousson A, White CR, Bullard DC, Brennan ML, Lusis AJ, Moore KP, Freeman BA. Baldus S, et al. Among authors: brennan ml. J Clin Invest. 2001 Dec;108(12):1759-70. doi: 10.1172/JCI12617. J Clin Invest. 2001. PMID: 11748259 Free PMC article.

5

A tale of two controversies: defining both the role of peroxidases in nitrotyrosine formation in vivo using eosinophil peroxidase and myeloperoxidase-deficient mice, and the nature of peroxidase-generated reactive nitrogen species.

Brennan ML, Wu W, Fu X, Shen Z, Song W, Frost H, Vadseth C, Narine L, Lenkiewicz E, Borchers MT, Lusis AJ, Lee JJ, Lee NA, Abu-Soud HM, Ischiropoulos H, Hazen SL. Brennan ML, et al. J Biol Chem. 2002 May 17;277(20):17415-27. doi: 10.1074/jbc.M112400200. Epub 2002 Feb 27. J Biol Chem. 2002. PMID: 11877405 Free article.

6

Myeloperoxidase, a leukocyte-derived vascular NO oxidase.

Eiserich JP, Baldus S, Brennan ML, Ma W, Zhang C, Tousson A, Castro L, Lusis AJ, Nauseef WM, White CR, Freeman BA. Eiserich JP, et al. Among authors: brennan ml. Science. 2002 Jun 28;296(5577):2391-4. doi: 10.1126/science.1106830. Science. 2002. PMID: 12089442

7

Myeloperoxidase-generated oxidants modulate left ventricular remodeling but not infarct size after myocardial infarction.

Vasilyev N, Williams T, Brennan ML, Unzek S, Zhou X, Heinecke JW, Spitz DR, Topol EJ, Hazen SL, Penn MS. Vasilyev N, et al. Among authors: brennan ml. Circulation. 2005 Nov 1;112(18):2812-20. doi: 10.1161/CIRCULATIONAHA.105.542340. Circulation. 2005. PMID: 16267254

8

Neutrophils and NADPH oxidase mediate intrapancreatic trypsin activation in murine experimental acute pancreatitis.

Gukovskaya AS, Vaquero E, Zaninovic V, Gorelick FS, Lusis AJ, Brennan ML, Holland S, Pandol SJ. Gukovskaya AS, et al. Among authors: brennan ml. Gastroenterology. 2002 Apr;122(4):974-84. doi: 10.1053/gast.2002.32409. Gastroenterology. 2002. PMID: 11910350

9

Blocking very late antigen-4 integrin decreases leukocyte entry and fatty streak formation in mice fed an atherogenic diet.

Shih PT, Brennan ML, Vora DK, Territo MC, Strahl D, Elices MJ, Lusis AJ, Berliner JA. Shih PT, et al. Among authors: brennan ml. Circ Res. 1999 Feb 19;84(3):345-51. doi: 10.1161/01.res.84.3.345. Circ Res. 1999. PMID: 10024309

10

Mildly oxidized LDL induces an increased apolipoprotein J/paraoxonase ratio.

Navab M, Hama-Levy S, Van Lenten BJ, Fonarow GC, Cardinez CJ, Castellani LW, Brennan ML, Lusis AJ, Fogelman AM, La Du BN. Navab M, et al. Among authors: brennan ml. J Clin Invest. 1997 Apr 15;99(8):2005-19. doi: 10.1172/JCI119369. J Clin Invest. 1997. PMID: 9109446 Free PMC article.

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