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Haplotypes and a novel defective allele of CES2 found in a Japanese population.
Kim SR, Sai K, Tanaka-Kagawa T, Jinno H, Ozawa S, Kaniwa N, Saito Y, Akasawa A, Matsumoto K, Saito H, Kamatani N, Shirao K, Yamamoto N, Yoshida T, Minami H, Ohtsu A, Saijo N, Sawada J. Kim SR, et al. Drug Metab Dispos. 2007 Oct;35(10):1865-72. doi: 10.1124/dmd.107.015339. Epub 2007 Jul 19. Drug Metab Dispos. 2007. PMID: 17640957 Clinical Trial.
Impact of CYP3A4 haplotypes on irinotecan pharmacokinetics in Japanese cancer patients.
Sai K, Saito Y, Fukushima-Uesaka H, Kurose K, Kaniwa N, Kamatani N, Shirao K, Yamamoto N, Hamaguchi T, Kunitoh H, Ohe Y, Tamura T, Yamada Y, Minami H, Ohtsu A, Yoshida T, Saijo N, Sawada J. Sai K, et al. Cancer Chemother Pharmacol. 2008 Aug;62(3):529-37. doi: 10.1007/s00280-007-0634-1. Epub 2007 Nov 8. Cancer Chemother Pharmacol. 2008. PMID: 17992531
Close association of UGT1A9 IVS1+399C>T with UGT1A1*28, *6, or *60 haplotype and its apparent influence on 7-ethyl-10-hydroxycamptothecin (SN-38) glucuronidation in Japanese.
Saito Y, Sai K, Maekawa K, Kaniwa N, Shirao K, Hamaguchi T, Yamamoto N, Kunitoh H, Ohe Y, Yamada Y, Tamura T, Yoshida T, Minami H, Ohtsu A, Matsumura Y, Saijo N, Sawada J. Saito Y, et al. Drug Metab Dispos. 2009 Feb;37(2):272-6. doi: 10.1124/dmd.108.024208. Epub 2008 Nov 3. Drug Metab Dispos. 2009. PMID: 18981166
316 results