Zhang Z - Search Results

1

Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction.

Hegde R, Srinivasula SM, Zhang Z, Wassell R, Mukattash R, Cilenti L, DuBois G, Lazebnik Y, Zervos AS, Fernandes-Alnemri T, Alnemri ES. Hegde R, et al. Among authors: zhang z. J Biol Chem. 2002 Jan 4;277(1):432-8. doi: 10.1074/jbc.M109721200. Epub 2001 Oct 17. J Biol Chem. 2002. PMID: 11606597 Free article.

2

The PYRIN-CARD protein ASC is an activating adaptor for caspase-1.

Srinivasula SM, Poyet JL, Razmara M, Datta P, Zhang Z, Alnemri ES. Srinivasula SM, et al. Among authors: zhang z. J Biol Chem. 2002 Jun 14;277(24):21119-22. doi: 10.1074/jbc.C200179200. Epub 2002 Apr 19. J Biol Chem. 2002. PMID: 11967258 Free article.

3

Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi.

Li W, Srinivasula SM, Chai J, Li P, Wu JW, Zhang Z, Alnemri ES, Shi Y. Li W, et al. Among authors: zhang z. Nat Struct Biol. 2002 Jun;9(6):436-41. doi: 10.1038/nsb795. Nat Struct Biol. 2002. PMID: 11967569

4

Inhibitor of apoptosis proteins are substrates for the mitochondrial serine protease Omi/HtrA2.

Srinivasula SM, Gupta S, Datta P, Zhang Z, Hegde R, Cheong N, Fernandes-Alnemri T, Alnemri ES. Srinivasula SM, et al. Among authors: zhang z. J Biol Chem. 2003 Aug 22;278(34):31469-72. doi: 10.1074/jbc.C300240200. Epub 2003 Jun 30. J Biol Chem. 2003. PMID: 12835328 Free article.

5

The polypeptide chain-releasing factor GSPT1/eRF3 is proteolytically processed into an IAP-binding protein.

Hegde R, Srinivasula SM, Datta P, Madesh M, Wassell R, Zhang Z, Cheong N, Nejmeh J, Fernandes-Alnemri T, Hoshino S, Alnemri ES. Hegde R, et al. Among authors: zhang z. J Biol Chem. 2003 Oct 3;278(40):38699-706. doi: 10.1074/jbc.M303179200. Epub 2003 Jul 15. J Biol Chem. 2003. PMID: 12865429 Free article.

6

Tim50, a component of the mitochondrial translocator, regulates mitochondrial integrity and cell death.

Guo Y, Cheong N, Zhang Z, De Rose R, Deng Y, Farber SA, Fernandes-Alnemri T, Alnemri ES. Guo Y, et al. Among authors: zhang z. J Biol Chem. 2004 Jun 4;279(23):24813-25. doi: 10.1074/jbc.M402049200. Epub 2004 Mar 25. J Biol Chem. 2004. PMID: 15044455 Free article.

7

The C-terminal tail of presenilin regulates Omi/HtrA2 protease activity.

Gupta S, Singh R, Datta P, Zhang Z, Orr C, Lu Z, Dubois G, Zervos AS, Meisler MH, Srinivasula SM, Fernandes-Alnemri T, Alnemri ES. Gupta S, et al. Among authors: zhang z. J Biol Chem. 2004 Oct 29;279(44):45844-54. doi: 10.1074/jbc.M404940200. Epub 2004 Aug 4. J Biol Chem. 2004. PMID: 15294909 Free article.

8

sickle, a novel Drosophila death gene in the reaper/hid/grim region, encodes an IAP-inhibitory protein.

Srinivasula SM, Datta P, Kobayashi M, Wu JW, Fujioka M, Hegde R, Zhang Z, Mukattash R, Fernandes-Alnemri T, Shi Y, Jaynes JB, Alnemri ES. Srinivasula SM, et al. Among authors: zhang z. Curr Biol. 2002 Jan 22;12(2):125-30. doi: 10.1016/s0960-9822(01)00657-1. Curr Biol. 2002. PMID: 11818063 Free PMC article.

9

Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice.

Jones JM, Datta P, Srinivasula SM, Ji W, Gupta S, Zhang Z, Davies E, Hajnóczky G, Saunders TL, Van Keuren ML, Fernandes-Alnemri T, Meisler MH, Alnemri ES. Jones JM, et al. Among authors: zhang z. Nature. 2003 Oct 16;425(6959):721-7. doi: 10.1038/nature02052. Epub 2003 Oct 8. Nature. 2003. PMID: 14534547 Free article.

10

Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells.

Wang JL, Liu D, Zhang ZJ, Shan S, Han X, Srinivasula SM, Croce CM, Alnemri ES, Huang Z. Wang JL, et al. Among authors: zhang zj. Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):7124-9. doi: 10.1073/pnas.97.13.7124. Proc Natl Acad Sci U S A. 2000. PMID: 10860979 Free PMC article.

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