Gibbs JB - Search Results

1

Chemistry and Biology of Cylindrols: Novel Inhibitors of Ras Farnesyl-Protein Transferase from Cylindrocarpon lucidum.

Singh SB, Ball RG, Bills GF, Cascales C, Gibbs JB, Goetz MA, Hoogsteen K, Jenkins RG, Liesch JM, Lingham RB, Silverman KC, Zink DL. Singh SB, et al. Among authors: gibbs jb. J Org Chem. 1996 Nov 1;61(22):7727-7737. doi: 10.1021/jo961074p. J Org Chem. 1996. PMID: 11667727

2

Clavaric acid and steroidal analogues as Ras- and FPP-directed inhibitors of human farnesyl-protein transferase.

Lingham RB, Silverman KC, Jayasuriya H, Kim BM, Amo SE, Wilson FR, Rew DJ, Schaber MD, Bergstrom JD, Koblan KS, Graham SL, Kohl NE, Gibbs JB, Singh SB. Lingham RB, et al. Among authors: gibbs jb. J Med Chem. 1998 Nov 5;41(23):4492-501. doi: 10.1021/jm980356+. J Med Chem. 1998. PMID: 9804689

3

Selective inhibition of farnesyl-protein transferase blocks ras processing in vivo.

Gibbs JB, Pompliano DL, Mosser SD, Rands E, Lingham RB, Singh SB, Scolnick EM, Kohl NE, Oliff A. Gibbs JB, et al. J Biol Chem. 1993 Apr 15;268(11):7617-20. J Biol Chem. 1993. PMID: 8463291 Free article.

4

Polyisoprenylation of Ras in vitro by a farnesyl-protein transferase.

Schaber MD, O'Hara MB, Garsky VM, Mosser SC, Bergstrom JD, Moores SL, Marshall MS, Friedman PA, Dixon RA, Gibbs JB. Schaber MD, et al. Among authors: gibbs jb. J Biol Chem. 1990 Sep 5;265(25):14701-4. J Biol Chem. 1990. PMID: 2203759 Free article.

5

Design and in vivo analysis of potent non-thiol inhibitors of farnesyl protein transferase.

Anthony NJ, Gomez RP, Schaber MD, Mosser SD, Hamilton KA, O'Neil TJ, Koblan KS, Graham SL, Hartman GD, Shah D, Rands E, Kohl NE, Gibbs JB, Oliff AI. Anthony NJ, et al. Among authors: gibbs jb. J Med Chem. 1999 Aug 26;42(17):3356-68. doi: 10.1021/jm990080l. J Med Chem. 1999. PMID: 10464022

6

Biochemical and biological analyses of farnesyl-protein transferase inhibitors.

Kohl NE, Koblan KS, Omer CA, Oliff A, Gibbs JB. Kohl NE, et al. Among authors: gibbs jb. Methods Mol Biol. 1998;84:283-91. doi: 10.1385/0-89603-488-7:283. Methods Mol Biol. 1998. PMID: 9666457

7

Non-thiol 3-aminomethylbenzamide inhibitors of farnesyl-protein transferase.

Ciccarone TM, MacTough SC, Williams TM, Dinsmore CJ, O'Neill TJ, Shah D, Culberson JC, Koblan KS, Kohl NE, Gibbs JB, Oliff AI, Graham SL, Hartman GD. Ciccarone TM, et al. Among authors: gibbs jb. Bioorg Med Chem Lett. 1999 Jul 19;9(14):1991-6. doi: 10.1016/s0960-894x(99)00323-6. Bioorg Med Chem Lett. 1999. PMID: 10450968

8

Synthesis and biological activity of ras farnesyl protein transferase inhibitors. Tetrapeptide analogs with amino methyl and carbon linkages.

Wai JS, Bamberger DL, Fisher TE, Graham SL, Smith RL, Gibbs JB, Mosser SD, Oliff AI, Pompliano DL, Rands E, et al. Wai JS, et al. Among authors: gibbs jb. Bioorg Med Chem. 1994 Sep;2(9):939-47. doi: 10.1016/s0968-0896(00)82043-x. Bioorg Med Chem. 1994. PMID: 7712129

9

Imidazole-containing diarylether and diarylsulfone inhibitors of farnesyl-protein transferase.

Dinsmore CJ, Williams TM, O'Neill TJ, Liu D, Rands E, Culberson JC, Lobell RB, Koblan KS, Kohl NE, Gibbs JB, Oliff AI, Graham SL, Hartman GD. Dinsmore CJ, et al. Among authors: gibbs jb. Bioorg Med Chem Lett. 1999 Dec 6;9(23):3301-6. doi: 10.1016/s0960-894x(99)00605-8. Bioorg Med Chem Lett. 1999. PMID: 10612589

10

Steady-state kinetic mechanism of Ras farnesyl:protein transferase.

Pompliano DL, Rands E, Schaber MD, Mosser SD, Anthony NJ, Gibbs JB. Pompliano DL, et al. Among authors: gibbs jb. Biochemistry. 1992 Apr 21;31(15):3800-7. doi: 10.1021/bi00130a010. Biochemistry. 1992. PMID: 1567835

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