Skerlj R - Search Results

1

Studies Directed toward the Synthesis of the Unusual Antileukemic Diterpene Jatrophatrione. 1. A Solution to the Problem of Chirality Merger during Elaboration of the Entire Carbotricyclic Framework.

Paquette LA, Nakatani S, Zydowsky TM, Edmondson SD, Sun LQ, Skerlj R. Paquette LA, et al. Among authors: skerlj r. J Org Chem. 1999 Apr 30;64(9):3244-3254. doi: 10.1021/jo9825254. J Org Chem. 1999. PMID: 11674427

2

Practical synthesis of the new carbapenem antibiotic ertapenem sodium.

Williams JM, Brands KM, Skerlj RT, Jobson RB, Marchesini G, Conrad KM, Pipik B, Savary KA, Tsay FR, Houghton PG, Sidler DR, Dolling UH, DiMichele LM, Novak TJ. Williams JM, et al. J Org Chem. 2005 Sep 16;70(19):7479-87. doi: 10.1021/jo0501442. J Org Chem. 2005. PMID: 16149774

3

Palladium(0)-catalyzed coupling of organozinc iodide reagents with bromopyridines: synthesis of selectively protected pyridine-containing azamacrocycles.

Skerlj RT, Zhou Y, Wilson T, Bridger GJ. Skerlj RT, et al. J Org Chem. 2002 Feb 22;67(4):1407-10. doi: 10.1021/jo0109523. J Org Chem. 2002. PMID: 11846698

4

Spontaneous enzymatically mediated dynamic kinetic resolution of 8-amino-5,6,7,8-tetrahydroquinoline.

Crawford JB, Skerlj RT, Bridger GJ. Crawford JB, et al. J Org Chem. 2007 Jan 19;72(2):669-71. doi: 10.1021/jo062037t. J Org Chem. 2007. PMID: 17221995

5

Enzymatic resolution of bicyclic 1-heteroarylamines using Candida antarctica lipase B.

Skupinska KA, McEachern EJ, Baird IR, Skerlj RT, Bridger GJ. Skupinska KA, et al. Among authors: skerlj rt. J Org Chem. 2003 May 2;68(9):3546-51. doi: 10.1021/jo026701r. J Org Chem. 2003. PMID: 12713358

6

Concise preparation of amino-5,6,7,8-tetrahydroquinolines and amino-5,6,7,8-tetrahydroisoquinolines via catalytic hydrogenation of acetamidoquinolines and acetamidoisoquinolines.

Skupinska KA, McEachern EJ, Skerlj RT, Bridger GJ. Skupinska KA, et al. J Org Chem. 2002 Nov 1;67(22):7890-3. doi: 10.1021/jo026258k. J Org Chem. 2002. PMID: 12398523

7

Ruthenium(III) polyaminocarboxylate complexes: efficient and effective nitric oxide scavengers.

Cameron BR, Darkes MC, Yee H, Olsen M, Fricker SP, Skerlj RT, Bridger GJ, Davies NA, Wilson MT, Rose DJ, Zubieta J. Cameron BR, et al. Among authors: skerlj rt. Inorg Chem. 2003 Mar 24;42(6):1868-76. doi: 10.1021/ic020219+. Inorg Chem. 2003. PMID: 12639119

8

Molecular mechanism of action of monocyclam versus bicyclam non-peptide antagonists in the CXCR4 chemokine receptor.

Rosenkilde MM, Gerlach LO, Hatse S, Skerlj RT, Schols D, Bridger GJ, Schwartz TW. Rosenkilde MM, et al. J Biol Chem. 2007 Sep 14;282(37):27354-27365. doi: 10.1074/jbc.M704739200. Epub 2007 Jun 28. J Biol Chem. 2007. PMID: 17599916 Free article.

9

Synthesis and structure-activity relationships of phenylenebis(methylene)-linked bis-azamacrocycles that inhibit HIV-1 and HIV-2 replication by antagonism of the chemokine receptor CXCR4.

Bridger GJ, Skerlj RT, Padmanabhan S, Martellucci SA, Henson GW, Struyf S, Witvrouw M, Schols D, De Clercq E. Bridger GJ, et al. Among authors: skerlj rt. J Med Chem. 1999 Sep 23;42(19):3971-81. doi: 10.1021/jm990211i. J Med Chem. 1999. PMID: 10508445

10

Synthesis and structure-activity relationships of azamacrocyclic C-X-C chemokine receptor 4 antagonists: analogues containing a single azamacrocyclic ring are potent inhibitors of T-cell tropic (X4) HIV-1 replication.

Bridger GJ, Skerlj RT, Hernandez-Abad PE, Bogucki DE, Wang Z, Zhou Y, Nan S, Boehringer EM, Wilson T, Crawford J, Metz M, Hatse S, Princen K, De Clercq E, Schols D. Bridger GJ, et al. J Med Chem. 2010 Feb 11;53(3):1250-60. doi: 10.1021/jm901530b. J Med Chem. 2010. PMID: 20043638

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