Jones DT - Search Results

1

Caspase 8 activation independent of Fas (CD95/APO-1) signaling may mediate killing of B-chronic lymphocytic leukemia cells by cytotoxic drugs or gamma radiation.

Jones DT, Ganeshaguru K, Virchis AE, Folarin NI, Lowdell MW, Mehta AB, Prentice HG, Hoffbrand AV, Wickremasinghe RG. Jones DT, et al. Blood. 2001 Nov 1;98(9):2800-7. doi: 10.1182/blood.v98.9.2800. Blood. 2001. PMID: 11675354 Free article.

2

Actions of the selective protein kinase C inhibitor PKC412 on B-chronic lymphocytic leukemia cells in vitro.

Ganeshaguru K, Wickremasinghe RG, Jones DT, Gordon M, Hart SM, Virchis AE, Prentice HG, Hoffbrand AV, Man A, Champain K, Csermak K, Mehta AB. Ganeshaguru K, et al. Among authors: jones dt. Haematologica. 2002 Feb;87(2):167-76. Haematologica. 2002. PMID: 11836167

3

Albumin activates the AKT signaling pathway and protects B-chronic lymphocytic leukemia cells from chlorambucil- and radiation-induced apoptosis.

Jones DT, Ganeshaguru K, Anderson RJ, Jackson TR, Bruckdorfer KR, Low SY, Palmqvist L, Prentice HG, Hoffbrand AV, Mehta AB, Wickremasinghe RG. Jones DT, et al. Blood. 2003 Apr 15;101(8):3174-80. doi: 10.1182/blood-2002-07-2143. Epub 2002 Dec 12. Blood. 2003. PMID: 12480711 Free article.

4

Cytotoxic drugs enhance the ex vivo sensitivity of malignant cells from a subset of acute myeloid leukaemia patients to apoptosis induction by tumour necrosis factor receptor-related apoptosis-inducing ligand.

Jones DT, Ganeshaguru K, Mitchell WA, Foroni L, Baker RJ, Prentice HG, Mehta AB, Wickremasinghe RG. Jones DT, et al. Br J Haematol. 2003 Jun;121(5):713-20. doi: 10.1046/j.1365-2141.2003.04340.x. Br J Haematol. 2003. PMID: 12780785 Free article.

5

Geldanamycin and herbimycin A induce apoptotic killing of B chronic lymphocytic leukemia cells and augment the cells' sensitivity to cytotoxic drugs.

Jones DT, Addison E, North JM, Lowdell MW, Hoffbrand AV, Mehta AB, Ganeshaguru K, Folarin NI, Wickremasinghe RG. Jones DT, et al. Blood. 2004 Mar 1;103(5):1855-61. doi: 10.1182/blood-2003-05-1603. Epub 2003 Oct 23. Blood. 2004. PMID: 14576064 Free article.

6

Autologous plasma activates Akt/protein kinase B and enhances basal survival and resistance to DNA damage-induced apoptosis in B-chronic lymphocytic leukaemia cells.

Wickremasinghe RG, Ganeshaguru K, Jones DT, Lindsay C, Spanswick VJ, Hartley JA, Wadhwa M, Thorpe R, Hoffbrand AV, Prentice HG, Mehta AB. Wickremasinghe RG, et al. Among authors: jones dt. Br J Haematol. 2001 Sep;114(3):608-15. doi: 10.1046/j.1365-2141.2001.02978.x. Br J Haematol. 2001. PMID: 11552986 Free article.

7

The sesquiterpene lactone parthenolide induces selective apoptosis of B-chronic lymphocytic leukemia cells in vitro.

Steele AJ, Jones DT, Ganeshaguru K, Duke VM, Yogashangary BC, North JM, Lowdell MW, Kottaridis PD, Mehta AB, Prentice AG, Hoffbrand AV, Wickremasinghe RG. Steele AJ, et al. Among authors: jones dt. Leukemia. 2006 Jun;20(6):1073-9. doi: 10.1038/sj.leu.2404230. Leukemia. 2006. PMID: 16628188

8

Human bone marrow stromal cells prevent apoptosis and support the survival of chronic lymphocytic leukaemia cells in vitro.

Panayiotidis P, Jones D, Ganeshaguru K, Foroni L, Hoffbrand AV. Panayiotidis P, et al. Br J Haematol. 1996 Jan;92(1):97-103. doi: 10.1046/j.1365-2141.1996.00305.x. Br J Haematol. 1996. PMID: 8562418

9

A novel treatment approach for low grade lymphoproliferative disorders using PKC412 (CGP41251), an inhibitor of protein kinase C.

Virchis A, Ganeshaguru K, Hart S, Jones D, Fletcher L, Wright F, Wickremasinghe R, Man A, Csermak K, Meyer T, Fabbro D, Champain K, Yap A, Prentice HG, Mehta A. Virchis A, et al. Hematol J. 2002;3(3):131-6. doi: 10.1038/sj.thj.6200165. Hematol J. 2002. PMID: 12111648 Clinical Trial.

10

Clinical effects and P-glycoprotein inhibition in patients with acute myeloid leukemia treated with zosuquidar trihydrochloride, daunorubicin and cytarabine.

Gerrard G, Payne E, Baker RJ, Jones DT, Potter M, Prentice HG, Ethell M, McCullough H, Burgess M, Mehta AB, Ganeshaguru K. Gerrard G, et al. Among authors: jones dt. Haematologica. 2004 Jul;89(7):782-90. Haematologica. 2004. PMID: 15257929 Clinical Trial.

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