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Page 1
Design and synthesis of potent and selective inhibitors of integrin VLA-4.
Wattanasin S, Weidmann B, Roche D, Myers S, Xing A, Guo Q, Sabio M, von Matt P, Hugo R, Maida S, Lake P, Weetall M. Wattanasin S, et al. Among authors: weidmann b. Bioorg Med Chem Lett. 2001 Nov 19;11(22):2955-8. doi: 10.1016/s0960-894x(01)00586-8. Bioorg Med Chem Lett. 2001. PMID: 11677134
Peptide deformylase inhibitors as potent antimycobacterial agents.
Teo JW, Thayalan P, Beer D, Yap AS, Nanjundappa M, Ngew X, Duraiswamy J, Liung S, Dartois V, Schreiber M, Hasan S, Cynamon M, Ryder NS, Yang X, Weidmann B, Bracken K, Dick T, Mukherjee K. Teo JW, et al. Among authors: weidmann b. Antimicrob Agents Chemother. 2006 Nov;50(11):3665-73. doi: 10.1128/AAC.00555-06. Epub 2006 Sep 11. Antimicrob Agents Chemother. 2006. PMID: 16966397 Free PMC article.
A collaborative hit-to-lead investigation leveraging medicinal chemistry expertise with high throughput library design, synthesis and purification capabilities.
Yang X, Parker D, Whitehead L, Ryder NS, Weidmann B, Stabile-Harris M, Kizer D, McKinnon M, Smellie A, Powers D. Yang X, et al. Among authors: weidmann b. Comb Chem High Throughput Screen. 2006 Feb;9(2):123-30. doi: 10.2174/138620706775541891. Comb Chem High Throughput Screen. 2006. PMID: 16475970
N-alkyl urea hydroxamic acids as a new class of peptide deformylase inhibitors with antibacterial activity.
Hackbarth CJ, Chen DZ, Lewis JG, Clark K, Mangold JB, Cramer JA, Margolis PS, Wang W, Koehn J, Wu C, Lopez S, Withers G 3rd, Gu H, Dunn E, Kulathila R, Pan SH, Porter WL, Jacobs J, Trias J, Patel DV, Weidmann B, White RJ, Yuan Z. Hackbarth CJ, et al. Among authors: weidmann b. Antimicrob Agents Chemother. 2002 Sep;46(9):2752-64. doi: 10.1128/AAC.46.9.2752-2764.2002. Antimicrob Agents Chemother. 2002. PMID: 12183225 Free PMC article.
Role of the AcrAB-TolC efflux pump in determining susceptibility of Haemophilus influenzae to the novel peptide deformylase inhibitor LBM415.
Dean CR, Narayan S, Daigle DM, Dzink-Fox JL, Puyang X, Bracken KR, Dean KE, Weidmann B, Yuan Z, Jain R, Ryder NS. Dean CR, et al. Among authors: weidmann b. Antimicrob Agents Chemother. 2005 Aug;49(8):3129-35. doi: 10.1128/AAC.49.8.3129-3135.2005. Antimicrob Agents Chemother. 2005. PMID: 16048914 Free PMC article.
Peptide deformylase inhibitors as antibacterial agents: identification of VRC3375, a proline-3-alkylsuccinyl hydroxamate derivative, by using an integrated combinatorial and medicinal chemistry approach.
Chen D, Hackbarth C, Ni ZJ, Wu C, Wang W, Jain R, He Y, Bracken K, Weidmann B, Patel DV, Trias J, White RJ, Yuan Z. Chen D, et al. Among authors: weidmann b. Antimicrob Agents Chemother. 2004 Jan;48(1):250-61. doi: 10.1128/AAC.48.1.250-261.2004. Antimicrob Agents Chemother. 2004. PMID: 14693547 Free PMC article.
42 results