Liu KG - Search Results

1

Identification of a series of PPAR gamma/delta dual agonists via solid-phase parallel synthesis.

Liu KG, Lambert MH, Leesnitzer LM, Oliver W Jr, Ott RJ, Plunket KD, Stuart LW, Brown PJ, Willson TM, Sternbach DD. Liu KG, et al. Bioorg Med Chem Lett. 2001 Nov 19;11(22):2959-62. doi: 10.1016/s0960-894x(01)00596-0. Bioorg Med Chem Lett. 2001. PMID: 11677135

2

Identification of a series of oxadiazole-substituted alpha-isopropoxy phenylpropanoic acids with activity on PPARalpha, PPARgamma, and PPARdelta.

Liu KG, Smith JS, Ayscue AH, Henke BR, Lambert MH, Leesnitzer LM, Plunket KD, Willson TM, Sternbach DD. Liu KG, et al. Bioorg Med Chem Lett. 2001 Sep 3;11(17):2385-8. doi: 10.1016/s0960-894x(01)00458-9. Bioorg Med Chem Lett. 2001. PMID: 11527737

3

Synthesis and biological activity of L-tyrosine-based PPARgamma agonists with reduced molecular weight.

Liu KG, Lambert MH, Ayscue AH, Henke BR, Leesnitzer LM, Oliver WR Jr, Plunket KD, Xu HE, Sternbach DD, Willson TM. Liu KG, et al. Bioorg Med Chem Lett. 2001 Dec 17;11(24):3111-3. doi: 10.1016/s0960-894x(01)00649-7. Bioorg Med Chem Lett. 2001. PMID: 11720854

4

Discovery of a novel series of peroxisome proliferator-activated receptor alpha/gamma dual agonists for the treatment of type 2 diabetes and dyslipidemia.

Liu K, Xu L, Berger JP, Macnaul KL, Zhou G, Doebber TW, Forrest MJ, Moller DE, Jones AB. Liu K, et al. J Med Chem. 2005 Apr 7;48(7):2262-5. doi: 10.1021/jm048993p. J Med Chem. 2005. PMID: 15801817

5

Discovery of novel non-steroidal reverse indole mineralocorticoid receptor antagonists.

Ogawa AK, Bunte EV, Mal R, Lan P, Sun Z, Crespo A, Wiltsie J, Clemas J, Gibson J, Contino L, Lisnock J, Zhou G, Garcia-Calvo M, Jochnowitz N, Ma X, Pan Y, Brown P, Zamlynny B, Bateman T, Leung D, Xu L, Tong X, Liu K, Crook M, Sinclair P. Ogawa AK, et al. Bioorg Med Chem Lett. 2016 Jun 15;26(12):2866-2869. doi: 10.1016/j.bmcl.2016.04.052. Epub 2016 Apr 20. Bioorg Med Chem Lett. 2016. PMID: 27161805

6

Benzimidazolones: a new class of selective peroxisome proliferator-activated receptor γ (PPARγ) modulators.

Liu W, Lau F, Liu K, Wood HB, Zhou G, Chen Y, Li Y, Akiyama TE, Castriota G, Einstein M, Wang C, McCann ME, Doebber TW, Wu M, Chang CH, McNamara L, McKeever B, Mosley RT, Berger JP, Meinke PT. Liu W, et al. J Med Chem. 2011 Dec 22;54(24):8541-54. doi: 10.1021/jm201061j. Epub 2011 Nov 28. J Med Chem. 2011. PMID: 22070604

7

Discovery of a peroxisome proliferator activated receptor gamma (PPARgamma) modulator with balanced PPARalpha activity for the treatment of type 2 diabetes and dyslipidemia.

Liu W, Liu K, Wood HB, McCann ME, Doebber TW, Chang CH, Akiyama TE, Einstein M, Berger JP, Meinke PT. Liu W, et al. J Med Chem. 2009 Jul 23;52(14):4443-53. doi: 10.1021/jm900367w. J Med Chem. 2009. PMID: 19530681

8

Discovery of a potent, highly selective, and orally efficacious small-molecule activator of the insulin receptor.

Liu K, Xu L, Szalkowski D, Li Z, Ding V, Kwei G, Huskey S, Moller DE, Heck JV, Zhang BB, Jones AB. Liu K, et al. J Med Chem. 2000 Sep 21;43(19):3487-94. doi: 10.1021/jm000285q. J Med Chem. 2000. PMID: 11000003

9

Nocathiacin analogs: Synthesis and antibacterial activity of novel water-soluble amides.

Xu L, Farthing AK, Dropinski JF, Meinke PT, McCallum C, Leavitt PS, Hickey EJ, Colwell L, Barrett J, Liu K. Xu L, et al. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3531-5. doi: 10.1016/j.bmcl.2009.04.144. Epub 2009 May 5. Bioorg Med Chem Lett. 2009. PMID: 19447613

10

Synthesis and antibacterial activity of novel water-soluble nocathiacin analogs.

Xu L, Farthing AK, Dropinski JF, Meinke PT, McCallum C, Hickey E, Liu K. Xu L, et al. Bioorg Med Chem Lett. 2013 Jan 1;23(1):366-9. doi: 10.1016/j.bmcl.2012.10.065. Epub 2012 Oct 23. Bioorg Med Chem Lett. 2013. PMID: 23164707

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