Threadgill MD - Search Results

1

5-aminoisoquinolinone, a potent inhibitor of poly (adenosine 5'-diphosphate ribose) polymerase, reduces myocardial infarct size.

Wayman N, McDonald MC, Thompson AS, Threadgill MD, Thiemermann C. Wayman N, et al. Among authors: threadgill md. Eur J Pharmacol. 2001 Oct 26;430(1):93-100. doi: 10.1016/s0014-2999(01)01359-0. Eur J Pharmacol. 2001. PMID: 11698068

2

5-Aminoisoquinolinone reduces renal injury and dysfunction caused by experimental ischemia/reperfusion.

Chatterjee PK, Chatterjee BE, Pedersen H, Sivarajah A, McDonald MC, Mota-Filipe H, Brown PA, Stewart KN, Cuzzocrea S, Threadgill MD, Thiemermann C. Chatterjee PK, et al. Among authors: threadgill md. Kidney Int. 2004 Feb;65(2):499-509. doi: 10.1111/j.1523-1755.2004.00415.x. Kidney Int. 2004. PMID: 14717920 Free article.

3

Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase, in a rodent model of lung injury.

Cuzzocrea S, McDonald MC, Mazzon E, Dugo L, Serraino I, Threadgill M, Caputi AP, Thiemermann C. Cuzzocrea S, et al. Biochem Pharmacol. 2002 Jan 15;63(2):293-304. doi: 10.1016/s0006-2952(01)00864-4. Biochem Pharmacol. 2002. PMID: 11841805

4

Beneficial effects of 5-aminoisoquinolinone, a novel, potent, water-soluble, inhibitor of poly (ADP-ribose) polymerase, in a rat model of splanchnic artery occlusion and reperfusion.

Di Paola R, Genovese T, Caputi AP, Threadgill M, Thiemermann C, Cuzzocrea S. Di Paola R, et al. Eur J Pharmacol. 2004 May 25;492(2-3):203-10. doi: 10.1016/j.ejphar.2004.03.033. Eur J Pharmacol. 2004. PMID: 15178366

5

Effects of 5-aminoisoquinolinone, a water-soluble, potent inhibitor of the activity of poly (ADP-ribose) polymerase on the organ injury and dysfunction caused by haemorrhagic shock.

McDonald MC, Mota-Filipe H, Wright JA, Abdelrahman M, Threadgill MD, Thompson AS, Thiemermann C. McDonald MC, et al. Among authors: threadgill md. Br J Pharmacol. 2000 Jun;130(4):843-50. doi: 10.1038/sj.bjp.0703391. Br J Pharmacol. 2000. PMID: 10864891 Free PMC article.

6

Inhibitors of poly(ADP-ribose) polymerase modulate signal transduction pathways and the development of bleomycin-induced lung injury.

Genovese T, Mazzon E, Di Paola R, Muià C, Threadgill MD, Caputi AP, Thiemermann C, Cuzzocrea S. Genovese T, et al. Among authors: threadgill md. J Pharmacol Exp Ther. 2005 May;313(2):529-38. doi: 10.1124/jpet.104.080705. Epub 2005 Jan 11. J Pharmacol Exp Ther. 2005. PMID: 15644425

7

Inhibitors of poly(ADP-ribose) polymerase modulate signal transduction pathways and secondary damage in experimental spinal cord trauma.

Genovese T, Mazzon E, Muià C, Patel NS, Threadgill MD, Bramanti P, De Sarro A, Thiemermann C, Cuzzocrea S. Genovese T, et al. Among authors: threadgill md. J Pharmacol Exp Ther. 2005 Feb;312(2):449-57. doi: 10.1124/jpet.104.076711. Epub 2004 Sep 27. J Pharmacol Exp Ther. 2005. PMID: 15452194

8

5-Aminoisoquinolinone reduces colon injury by experimental colitis.

Cuzzocrea S, Mazzon E, Di Paola R, Genovese T, Patel NS, Muià C, Threadgill MD, De Sarro A, Thiemermann C. Cuzzocrea S, et al. Among authors: threadgill md. Naunyn Schmiedebergs Arch Pharmacol. 2004 Dec;370(6):464-73. doi: 10.1007/s00210-004-1002-x. Epub 2004 Nov 18. Naunyn Schmiedebergs Arch Pharmacol. 2004. PMID: 15599708

9

Synthesis of 4-alkyl-, 4-aryl- and 4-arylamino-5-aminoisoquinolin-1-ones and identification of a new PARP-2 selective inhibitor.

Sunderland PT, Dhami A, Mahon MF, Jones LA, Tully SR, Lloyd MD, Thompson AS, Javaid H, Martin NM, Threadgill MD. Sunderland PT, et al. Among authors: threadgill md. Org Biomol Chem. 2011 Feb 7;9(3):881-91. doi: 10.1039/c0ob00665c. Epub 2010 Dec 2. Org Biomol Chem. 2011. PMID: 21127791 Free article.

10

5-Benzamidoisoquinolin-1-ones and 5-(ω-carboxyalkyl)isoquinolin-1-ones as isoform-selective inhibitors of poly(ADP-ribose) polymerase 2 (PARP-2).

Sunderland PT, Woon EC, Dhami A, Bergin AB, Mahon MF, Wood PJ, Jones LA, Tully SR, Lloyd MD, Thompson AS, Javaid H, Martin NM, Threadgill MD. Sunderland PT, et al. Among authors: threadgill md. J Med Chem. 2011 Apr 14;54(7):2049-59. doi: 10.1021/jm1010918. Epub 2011 Mar 18. J Med Chem. 2011. PMID: 21417348 Free article.

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