Xiong L - Search Results

1

Binding site of macrolide antibiotics on the ribosome: new resistance mutation identifies a specific interaction of ketolides with rRNA.

Garza-Ramos G, Xiong L, Zhong P, Mankin A. Garza-Ramos G, et al. Among authors: xiong l. J Bacteriol. 2001 Dec;183(23):6898-907. doi: 10.1128/JB.183.23.6898-6907.2001. J Bacteriol. 2001. PMID: 11698379 Free PMC article.

2

Binding site of the bridged macrolides in the Escherichia coli ribosome.

Xiong L, Korkhin Y, Mankin AS. Xiong L, et al. Antimicrob Agents Chemother. 2005 Jan;49(1):281-8. doi: 10.1128/AAC.49.1.281-288.2005. Antimicrob Agents Chemother. 2005. PMID: 15616307 Free PMC article.

3

23S rRNA positions essential for tRNA binding in ribosomal functional sites.

Bocchetta M, Xiong L, Mankin AS. Bocchetta M, et al. Among authors: xiong l. Proc Natl Acad Sci U S A. 1998 Mar 31;95(7):3525-30. doi: 10.1073/pnas.95.7.3525. Proc Natl Acad Sci U S A. 1998. PMID: 9520399 Free PMC article.

4

A ketolide resistance mutation in domain II of 23S rRNA reveals the proximity of hairpin 35 to the peptidyl transferase centre.

Xiong L, Shah S, Mauvais P, Mankin AS. Xiong L, et al. Mol Microbiol. 1999 Jan;31(2):633-9. doi: 10.1046/j.1365-2958.1999.01203.x. Mol Microbiol. 1999. PMID: 10027979 Free article.

5

Resistance mutations in 23 S rRNA identify the site of action of the protein synthesis inhibitor linezolid in the ribosomal peptidyl transferase center.

Kloss P, Xiong L, Shinabarger DL, Mankin AS. Kloss P, et al. Among authors: xiong l. J Mol Biol. 1999 Nov 19;294(1):93-101. doi: 10.1006/jmbi.1999.3247. J Mol Biol. 1999. PMID: 10556031

6

Oxazolidinone resistance mutations in 23S rRNA of Escherichia coli reveal the central region of domain V as the primary site of drug action.

Xiong L, Kloss P, Douthwaite S, Andersen NM, Swaney S, Shinabarger DL, Mankin AS. Xiong L, et al. J Bacteriol. 2000 Oct;182(19):5325-31. doi: 10.1128/JB.182.19.5325-5331.2000. J Bacteriol. 2000. PMID: 10986233 Free PMC article.

7

Interactions between 23S rRNA and tRNA in the ribosomal E site.

Bocchetta M, Xiong L, Shah S, Mankin AS. Bocchetta M, et al. Among authors: xiong l. RNA. 2001 Jan;7(1):54-63. doi: 10.1017/s1355838201001650. RNA. 2001. PMID: 11214181 Free PMC article.

8

A novel site of antibiotic action in the ribosome: interaction of evernimicin with the large ribosomal subunit.

Belova L, Tenson T, Xiong L, McNicholas PM, Mankin AS. Belova L, et al. Among authors: xiong l. Proc Natl Acad Sci U S A. 2001 Mar 27;98(7):3726-31. doi: 10.1073/pnas.071527498. Epub 2001 Mar 20. Proc Natl Acad Sci U S A. 2001. PMID: 11259679 Free PMC article.

9

The critical role of the universally conserved A2602 of 23S ribosomal RNA in the release of the nascent peptide during translation termination.

Polacek N, Gomez MJ, Ito K, Xiong L, Nakamura Y, Mankin A. Polacek N, et al. Among authors: xiong l. Mol Cell. 2003 Jan;11(1):103-12. doi: 10.1016/s1097-2765(02)00825-0. Mol Cell. 2003. PMID: 12535525 Free article.

10

Acquisition of a natural resistance gene renders a clinical strain of methicillin-resistant Staphylococcus aureus resistant to the synthetic antibiotic linezolid.

Toh SM, Xiong L, Arias CA, Villegas MV, Lolans K, Quinn J, Mankin AS. Toh SM, et al. Among authors: xiong l. Mol Microbiol. 2007 Jun;64(6):1506-14. doi: 10.1111/j.1365-2958.2007.05744.x. Mol Microbiol. 2007. PMID: 17555436 Free PMC article.

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