Schaeffer EM - Search Results

1

Mutation of Tec family kinases alters T helper cell differentiation.

Schaeffer EM, Yap GS, Lewis CM, Czar MJ, McVicar DW, Cheever AW, Sher A, Schwartzberg PL. Schaeffer EM, et al. Nat Immunol. 2001 Dec;2(12):1183-8. doi: 10.1038/ni734. Nat Immunol. 2001. PMID: 11702066

2

rlk/TXK encodes two forms of a novel cysteine string tyrosine kinase activated by Src family kinases.

Debnath J, Chamorro M, Czar MJ, Schaeffer EM, Lenardo MJ, Varmus HE, Schwartzberg PL. Debnath J, et al. Among authors: schaeffer em. Mol Cell Biol. 1999 Feb;19(2):1498-507. doi: 10.1128/MCB.19.2.1498. Mol Cell Biol. 1999. PMID: 9891083 Free PMC article.

3

Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity.

Schaeffer EM, Debnath J, Yap G, McVicar D, Liao XC, Littman DR, Sher A, Varmus HE, Lenardo MJ, Schwartzberg PL. Schaeffer EM, et al. Science. 1999 Apr 23;284(5414):638-41. doi: 10.1126/science.284.5414.638. Science. 1999. PMID: 10213685

4

Tec family kinases in lymphocyte signaling and function.

Schaeffer EM, Schwartzberg PL. Schaeffer EM, et al. Curr Opin Immunol. 2000 Jun;12(3):282-8. doi: 10.1016/s0952-7915(00)00088-1. Curr Opin Immunol. 2000. PMID: 10781397 Review.

5

Tec family kinases modulate thresholds for thymocyte development and selection.

Schaeffer EM, Broussard C, Debnath J, Anderson S, McVicar DW, Schwartzberg PL. Schaeffer EM, et al. J Exp Med. 2000 Oct 2;192(7):987-1000. doi: 10.1084/jem.192.7.987. J Exp Med. 2000. PMID: 11015440 Free PMC article.

6

Biochemical and genetic analyses of the Tec kinases Itk and Rlk/Txk.

Czar MJ, Debnath J, Schaeffer EM, Lewis CM, Schwartzberg PL. Czar MJ, et al. Among authors: schaeffer em. Biochem Soc Trans. 2001 Nov;29(Pt 6):863-7. doi: 10.1042/0300-5127:0290863. Biochem Soc Trans. 2001. PMID: 11709089 Review.

7

PKC-theta is required for TCR-induced NF-kappaB activation in mature but not immature T lymphocytes.

Sun Z, Arendt CW, Ellmeier W, Schaeffer EM, Sunshine MJ, Gandhi L, Annes J, Petrzilka D, Kupfer A, Schwartzberg PL, Littman DR. Sun Z, et al. Among authors: schaeffer em. Nature. 2000 Mar 23;404(6776):402-7. doi: 10.1038/35006090. Nature. 2000. PMID: 10746729

8

Two Randomized Trials of Neutralizing Antibodies to Prevent HIV-1 Acquisition.

Corey L, Gilbert PB, Juraska M, Montefiori DC, Morris L, Karuna ST, Edupuganti S, Mgodi NM, deCamp AC, Rudnicki E, Huang Y, Gonzales P, Cabello R, Orrell C, Lama JR, Laher F, Lazarus EM, Sanchez J, Frank I, Hinojosa J, Sobieszczyk ME, Marshall KE, Mukwekwerere PG, Makhema J, Baden LR, Mullins JI, Williamson C, Hural J, McElrath MJ, Bentley C, Takuva S, Gomez Lorenzo MM, Burns DN, Espy N, Randhawa AK, Kochar N, Piwowar-Manning E, Donnell DJ, Sista N, Andrew P, Kublin JG, Gray G, Ledgerwood JE, Mascola JR, Cohen MS; HVTN 704/HPTN 085 and HVTN 703/HPTN 081 Study Teams. Corey L, et al. N Engl J Med. 2021 Mar 18;384(11):1003-1014. doi: 10.1056/NEJMoa2031738. N Engl J Med. 2021. PMID: 33730454 Free PMC article. Clinical Trial.

9

Prostate MRI and clinicopathologic risk calculator to predict laterality of extraprostatic extension at radical prostatectomy.

Li EV, Kumar S, Aguiar JA, Siddiqui MR, Sun Z, Neill C, Schaeffer EM, Ross AE, Patel HD. Li EV, et al. Among authors: schaeffer em. Prostate Cancer Prostatic Dis. 2025 Jan 7. doi: 10.1038/s41391-024-00928-7. Online ahead of print. Prostate Cancer Prostatic Dis. 2025. PMID: 39762550

10

Prostate Cancer Risk Stratification in NRG Oncology Phase III Randomized Trials Using Multimodal Deep Learning With Digital Histopathology.

Tward JD, Huang HC, Esteva A, Mohamad O, van der Wal D, Simko JP, DeVries S, Zhang J, Joun S, Showalter TN, Schaeffer EM, Morgan TM, Monson JM, Wallace JA, Bahary JP, Sandler HM, Spratt DE, Rodgers JP, Feng FY, Tran PT. Tward JD, et al. Among authors: schaeffer em. JCO Precis Oncol. 2024 Oct;8:e2400145. doi: 10.1200/PO.24.00145. Epub 2024 Oct 24. JCO Precis Oncol. 2024. PMID: 39447096 Free PMC article. Clinical Trial.

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