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Chronic cardiotoxicity of anticancer anthracyclines in the rat: role of secondary metabolites and reduced toxicity by a novel anthracycline with impaired metabolite formation and reactivity.
Sacco G, Giampietro R, Salvatorelli E, Menna P, Bertani N, Graiani G, Animati F, Goso C, Maggi CA, Manzini S, Minotti G. Sacco G, et al. Among authors: animati f. Br J Pharmacol. 2003 Jun;139(3):641-51. doi: 10.1038/sj.bjp.0705270. Br J Pharmacol. 2003. PMID: 12788824 Free PMC article.
Anthracycline metabolism and toxicity in human myocardium: comparisons between doxorubicin, epirubicin, and a novel disaccharide analogue with a reduced level of formation and [4Fe-4S] reactivity of its secondary alcohol metabolite.
Minotti G, Licata S, Saponiero A, Menna P, Calafiore AM, Di Giammarco G, Liberi G, Animati F, Cipollone A, Manzini S, Maggi CA. Minotti G, et al. Among authors: animati f. Chem Res Toxicol. 2000 Dec;13(12):1336-41. doi: 10.1021/tx000143z. Chem Res Toxicol. 2000. PMID: 11123976
New developments in antitumor anthracyclines.
Arcamone F, Animati F, Capranico G, Lombardi P, Pratesi G, Manzini S, Supino R, Zunino F. Arcamone F, et al. Among authors: animati f. Pharmacol Ther. 1997 Oct-Dec;76(1-3):117-24. doi: 10.1016/s0163-7258(97)00096-x. Pharmacol Ther. 1997. PMID: 9535173 Review.
Topoisomerase poisoning activity of novel disaccharide anthracyclines.
Guano F, Pourquier P, Tinelli S, Binaschi M, Bigioni M, Animati F, Manzini S, Zunino F, Kohlhagen G, Pommier Y, Capranico G. Guano F, et al. Among authors: animati f. Mol Pharmacol. 1999 Jul;56(1):77-84. doi: 10.1124/mol.56.1.77. Mol Pharmacol. 1999. PMID: 10385686
Doxorubicin disaccharide analogue: apoptosis-related improvement of efficacy in vivo.
Arcamone F, Animati F, Berettoni M, Bigioni M, Capranico G, Casazza AM, Caserini C, Cipollone A, De Cesare M, Franciotti M, Lombardi P, Madami A, Manzini S, Monteagudo E, Polizzi D, Pratesi G, Righetti SC, Salvatore C, Supino R, Zunino F. Arcamone F, et al. Among authors: animati f. J Natl Cancer Inst. 1997 Aug 20;89(16):1217-23. doi: 10.1093/jnci/89.16.1217. J Natl Cancer Inst. 1997. PMID: 9274917
Anthracyclines: selected new developments.
Binaschi M, Bigioni M, Cipollone A, Rossi C, Goso C, Maggi CA, Capranico G, Animati F. Binaschi M, et al. Among authors: animati f. Curr Med Chem Anticancer Agents. 2001 Aug;1(2):113-30. doi: 10.2174/1568011013354723. Curr Med Chem Anticancer Agents. 2001. PMID: 12678762 Review.
33 results