Harper-Wynne C - Search Results

1

HER-2 amplification impedes the antiproliferative effects of hormone therapy in estrogen receptor-positive primary breast cancer.

Dowsett M, Harper-Wynne C, Boeddinghaus I, Salter J, Hills M, Dixon M, Ebbs S, Gui G, Sacks N, Smith I. Dowsett M, et al. Cancer Res. 2001 Dec 1;61(23):8452-8. Cancer Res. 2001. PMID: 11731427

2

Anastrozole shows evidence of activity in postmenopausal patients who have responded or stabilised on formestane therapy.

Harper-Wynne C, Coombes RC. Harper-Wynne C, et al. Eur J Cancer. 1999 May;35(5):744-6. doi: 10.1016/s0959-8049(99)00015-5. Eur J Cancer. 1999. PMID: 10505035 Clinical Trial.

3

Aromatase inhibitors and their use in the sequential setting.

Coombes RC, Harper-Wynne C, Dowsett M. Coombes RC, et al. Endocr Relat Cancer. 1999 Jun;6(2):259-63. doi: 10.1677/erc.0.0060259. Endocr Relat Cancer. 1999. PMID: 10731118 Review.

4

Recent advances in the clinical application of aromatase inhibitors.

Harper-Wynne C, Dowsett M. Harper-Wynne C, et al. J Steroid Biochem Mol Biol. 2001 Jan-Mar;76(1-5):179-86. doi: 10.1016/s0960-0760(00)00150-3. J Steroid Biochem Mol Biol. 2001. PMID: 11384876 Review.

5

Comparison of the systemic and intratumoral effects of tamoxifen and the aromatase inhibitor vorozole in postmenopausal patients with primary breast cancer.

Harper-Wynne CL, Sacks NP, Shenton K, MacNeill FA, Sauven P, Laidlaw IJ, Rayter Z, Miall S, Howes A, Salter J, Hills MJ, Lowe FM, A'Hern R, Nasiri N, Doody D, Iqbal J, Dowsett M. Harper-Wynne CL, et al. J Clin Oncol. 2002 Feb 15;20(4):1026-35. doi: 10.1200/JCO.2002.20.4.1026. J Clin Oncol. 2002. PMID: 11844826 Clinical Trial.

6

Effects of the aromatase inhibitor letrozole on normal breast epithelial cell proliferation and metabolic indices in postmenopausal women: a pilot study for breast cancer prevention.

Harper-Wynne C, Ross G, Sacks N, Salter J, Nasiri N, Iqbal J, A'Hern R, Dowsett M. Harper-Wynne C, et al. Cancer Epidemiol Biomarkers Prev. 2002 Jul;11(7):614-21. Cancer Epidemiol Biomarkers Prev. 2002. PMID: 12101108 Clinical Trial.

7

Breast cancer.

Ring A, Harper-Wynne C, Smith I. Ring A, et al. Cancer Chemother Biol Response Modif. 2005;22:545-61. Cancer Chemother Biol Response Modif. 2005. PMID: 16110628 Review. No abstract available.

8

Impact of estrogen deprivation on gene expression profiles of normal postmenopausal breast tissue in vivo.

Kendall A, Anderson H, Dunbier AK, Mackay A, Dexter T, Urruticoechea A, Harper-Wynne C, Dowsett M. Kendall A, et al. Cancer Epidemiol Biomarkers Prev. 2008 Apr;17(4):855-63. doi: 10.1158/1055-9965.EPI-07-2718. Cancer Epidemiol Biomarkers Prev. 2008. PMID: 18398027

9

BRCA1 testing should be offered to individuals with triple-negative breast cancer diagnosed below 50 years.

Robertson L, Hanson H, Seal S, Warren-Perry M, Hughes D, Howell I, Turnbull C, Houlston R, Shanley S, Butler S, Evans DG, Ross G, Eccles D, Tutt A, Rahman N; TNT Trial TMG; BCSC (UK). Robertson L, et al. Br J Cancer. 2012 Mar 13;106(6):1234-8. doi: 10.1038/bjc.2012.31. Epub 2012 Feb 14. Br J Cancer. 2012. PMID: 22333603 Free PMC article.

10

Antiproliferative Effect of Lapatinib in HER2-Positive and HER2-Negative/HER3-High Breast Cancer: Results of the Presurgical Randomized MAPLE Trial (CRUK E/06/039).

Leary A, Evans A, Johnston SR, A'Hern R, Bliss JM, Sahoo R, Detre S, Haynes BP, Hills M, Harper-Wynne C, Bundred N, Coombes G, Smith I, Dowsett M. Leary A, et al. Clin Cancer Res. 2015 Jul 1;21(13):2932-40. doi: 10.1158/1078-0432.CCR-14-1428. Epub 2014 Nov 14. Clin Cancer Res. 2015. PMID: 25398453 Clinical Trial.

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