Royer WE Jr - Search Results

1

NADH/NAD⁺ binding and linked tetrameric assembly of the oncogenic transcription factors CtBP1 and CtBP2.

Erlandsen H, Jecrois AM, Nichols JC, Cole JL, Royer WE Jr. Erlandsen H, et al. Among authors: royer we jr. FEBS Lett. 2022 Feb;596(4):479-490. doi: 10.1002/1873-3468.14276. Epub 2022 Jan 17. FEBS Lett. 2022. PMID: 34997967 Free article.

2

NAD(H) phosphates mediate tetramer assembly of human C-terminal binding protein (CtBP).

Nichols JC, Schiffer CA, Royer WE Jr. Nichols JC, et al. Among authors: royer we jr. J Biol Chem. 2021 Jan-Jun;296:100351. doi: 10.1016/j.jbc.2021.100351. Epub 2021 Jan 30. J Biol Chem. 2021. PMID: 33524397 Free PMC article.

3

Cryo-EM structure of CtBP2 confirms tetrameric architecture.

Jecrois AM, Dcona MM, Deng X, Bandyopadhyay D, Grossman SR, Schiffer CA, Royer WE Jr. Jecrois AM, et al. Among authors: royer we jr. Structure. 2021 Apr 1;29(4):310-319.e5. doi: 10.1016/j.str.2020.11.008. Epub 2020 Dec 1. Structure. 2021. PMID: 33264605 Free PMC article.

4

Assembly of human C-terminal binding protein (CtBP) into tetramers.

Bellesis AG, Jecrois AM, Hayes JA, Schiffer CA, Royer WE Jr. Bellesis AG, et al. Among authors: royer we jr. J Biol Chem. 2018 Jun 8;293(23):9101-9112. doi: 10.1074/jbc.RA118.002514. Epub 2018 Apr 26. J Biol Chem. 2018. PMID: 29700119 Free PMC article.

5

Design, synthesis, and biological evaluation of substrate-competitive inhibitors of C-terminal Binding Protein (CtBP).

Korwar S, Morris BL, Parikh HI, Coover RA, Doughty TW, Love IM, Hilbert BJ, Royer WE Jr, Kellogg GE, Grossman SR, Ellis KC. Korwar S, et al. Among authors: royer we jr. Bioorg Med Chem. 2016 Jun 15;24(12):2707-15. doi: 10.1016/j.bmc.2016.04.037. Epub 2016 Apr 20. Bioorg Med Chem. 2016. PMID: 27156192 Free PMC article.

6

Structure-guided design of a high affinity inhibitor to human CtBP.

Hilbert BJ, Morris BL, Ellis KC, Paulsen JL, Schiffer CA, Grossman SR, Royer WE Jr. Hilbert BJ, et al. Among authors: royer we jr. ACS Chem Biol. 2015 Apr 17;10(4):1118-27. doi: 10.1021/cb500820b. Epub 2015 Jan 30. ACS Chem Biol. 2015. PMID: 25636004 Free PMC article.

7

Insight into the allosteric mechanism of Scapharca dimeric hemoglobin.

Laine JM, Amat M, Morgan BR, Royer WE Jr, Massi F. Laine JM, et al. Among authors: royer we jr. Biochemistry. 2014 Nov 25;53(46):7199-210. doi: 10.1021/bi500591s. Epub 2014 Nov 14. Biochemistry. 2014. PMID: 25356908 Free PMC article.

8

Crystal structures of human CtBP in complex with substrate MTOB reveal active site features useful for inhibitor design.

Hilbert BJ, Grossman SR, Schiffer CA, Royer WE Jr. Hilbert BJ, et al. Among authors: royer we jr. FEBS Lett. 2014 May 2;588(9):1743-8. doi: 10.1016/j.febslet.2014.03.026. Epub 2014 Mar 19. FEBS Lett. 2014. PMID: 24657618 Free PMC article.

9

Resolution of structural heterogeneity in dynamic crystallography.

Ren Z, Chan PW, Moffat K, Pai EF, Royer WE Jr, Šrajer V, Yang X. Ren Z, et al. Among authors: royer we jr. Acta Crystallogr D Biol Crystallogr. 2013 Jun;69(Pt 6):946-59. doi: 10.1107/S0907444913003454. Epub 2013 May 2. Acta Crystallogr D Biol Crystallogr. 2013. PMID: 23695239 Free PMC article.

10

Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures.

Ren Z, Srajer V, Knapp JE, Royer WE Jr. Ren Z, et al. Among authors: royer we jr. Proc Natl Acad Sci U S A. 2012 Jan 3;109(1):107-12. doi: 10.1073/pnas.1109213108. Epub 2011 Dec 14. Proc Natl Acad Sci U S A. 2012. PMID: 22171006 Free PMC article.

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