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Semaphorin3A signalling is mediated via sequential Cdk5 and GSK3beta phosphorylation of CRMP2: implication of common phosphorylating mechanism underlying axon guidance and Alzheimer's disease.
Uchida Y, Ohshima T, Sasaki Y, Suzuki H, Yanai S, Yamashita N, Nakamura F, Takei K, Ihara Y, Mikoshiba K, Kolattukudy P, Honnorat J, Goshima Y. Uchida Y, et al. Among authors: ihara y. Genes Cells. 2005 Feb;10(2):165-79. doi: 10.1111/j.1365-2443.2005.00827.x. Genes Cells. 2005. PMID: 15676027 Free article.
Modulation of lipid kinase PI4KIIα activity and lipid raft association of presenilin 1 underlies γ-secretase inhibition by ginsenoside (20S)-Rg3.
Kang MS, Baek SH, Chun YS, Moore AZ, Landman N, Berman D, Yang HO, Morishima-Kawashima M, Osawa S, Funamoto S, Ihara Y, Di Paolo G, Park JH, Chung S, Kim TW. Kang MS, et al. Among authors: ihara y. J Biol Chem. 2013 Jul 19;288(29):20868-20882. doi: 10.1074/jbc.M112.445734. Epub 2013 May 30. J Biol Chem. 2013. PMID: 23723072 Free PMC article.
Random mutagenesis of presenilin-1 identifies novel mutants exclusively generating long amyloid beta-peptides.
Nakaya Y, Yamane T, Shiraishi H, Wang HQ, Matsubara E, Sato T, Dolios G, Wang R, De Strooper B, Shoji M, Komano H, Yanagisawa K, Ihara Y, Fraser P, St George-Hyslop P, Nishimura M. Nakaya Y, et al. Among authors: ihara y. J Biol Chem. 2005 May 13;280(19):19070-7. doi: 10.1074/jbc.M501130200. Epub 2005 Mar 10. J Biol Chem. 2005. PMID: 15764596 Free article.
718 results