Scott KR - Search Results

1

Influence of multidrug resistance (MDR) proteins at the blood-brain barrier on the transport and brain distribution of enaminone anticonvulsants.

Cox DS, Scott KR, Gao H, Raje S, Eddington ND. Cox DS, et al. Among authors: scott kr. J Pharm Sci. 2001 Oct;90(10):1540-52. doi: 10.1002/jps.1104. J Pharm Sci. 2001. PMID: 11745712

2

Effect of P-glycoprotein on the pharmacokinetics and tissue distribution of enaminone anticonvulsants: analysis by population and physiological approaches.

Cox DS, Scott KR, Gao H, Eddington ND. Cox DS, et al. Among authors: scott kr. J Pharmacol Exp Ther. 2002 Sep;302(3):1096-104. doi: 10.1124/jpet.102.035436. J Pharmacol Exp Ther. 2002. PMID: 12183668

3

The influence of enaminones on the transport and oral bioavailability of P-glycoprotein substrate therapeutic agents.

Salama NN, Scott KR, Eddington ND. Salama NN, et al. Among authors: scott kr. Int J Pharm. 2004 Apr 1;273(1-2):135-47. doi: 10.1016/j.ijpharm.2003.12.020. Int J Pharm. 2004. PMID: 15010138

4

DM27, an enaminone, modifies the in vitro transport of antiviral therapeutic agents.

Salama NN, Scott KR, Eddington ND. Salama NN, et al. Among authors: scott kr. Biopharm Drug Dispos. 2004 Jul;25(5):227-36. doi: 10.1002/bdd.404. Biopharm Drug Dispos. 2004. PMID: 15248192

5

Determination of the enaminone DM5, an anti-epileptic agent, in mouse plasma and brain tissue by high-performance liquid chromatography with ultraviolet detection.

Cox DS, Du J, Scott KR, Gao H, Eddington ND. Cox DS, et al. Among authors: scott kr. J Chromatogr B Biomed Sci Appl. 2000 Dec 1;749(2):191-6. doi: 10.1016/s0378-4347(00)00411-4. J Chromatogr B Biomed Sci Appl. 2000. PMID: 11145056

6

Enhancing the permeation of marker compounds and enaminone anticonvulsants across Caco-2 monolayers by modulating tight junctions using zonula occludens toxin.

Cox DS, Gao H, Raje S, Scott KR, Eddington ND. Cox DS, et al. Among authors: scott kr. Eur J Pharm Biopharm. 2001 Sep;52(2):145-50. doi: 10.1016/s0939-6411(01)00172-2. Eur J Pharm Biopharm. 2001. PMID: 11522479

7

Multidrug resistance and anticonvulsants: new studies with some enaminones.

Salama NN, Eddington ND, Payne D, Wilsonb TL, Scott KR. Salama NN, et al. Among authors: scott kr. Curr Med Chem. 2004 Aug;11(15):2093-113. doi: 10.2174/0929867043364766. Curr Med Chem. 2004. PMID: 15279569 Review.

8

Preclinical evaluation of the pharmacokinetics, brain uptake and metabolism of E121, an antiepileptic enaminone ester, in rats.

Khurana M, Salama NN, Scott KR, Nemieboka NN, Bauer KS Jr, Eddington ND. Khurana M, et al. Among authors: scott kr. Biopharm Drug Dispos. 2003 Dec;24(9):397-407. doi: 10.1002/bdd.376. Biopharm Drug Dispos. 2003. PMID: 14689468

9

Enaminones-versatile therapeutic pharmacophores. Further advances.

Eddington ND, Cox DS, Roberts RR, Stables JP, Powell CB, Scott KR. Eddington ND, et al. Among authors: scott kr. Curr Med Chem. 2000 Apr;7(4):417-36. doi: 10.2174/0929867003375092. Curr Med Chem. 2000. PMID: 10702617 Review.

10

Synthesis and anticonvulsant activity of enaminones. 4. Investigations on isoxazole derivatives.

Eddington ND, Cox DS, Roberts RR, Butcher RJ, Edafiogho IO, Stables JP, Cooke N, Goodwin AM, Smith CA, Scott KR. Eddington ND, et al. Among authors: scott kr. Eur J Med Chem. 2002 Aug;37(8):635-48. doi: 10.1016/s0223-5234(02)01377-6. Eur J Med Chem. 2002. PMID: 12161061

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