Ertl PF - Search Results

1

Design and synthesis of pyrrolidine-5,5-trans-lactams (5-oxohexahydropyrrolo[3,2-b]pyrroles) as novel mechanism-based inhibitors of human cytomegalovirus protease. 2. Potency and chirality.

Borthwick AD, Crame AJ, Ertl PF, Exall AM, Haley TM, Hart GJ, Mason AM, Pennell AM, Singh OM, Weingarten GG, Woolven JM. Borthwick AD, et al. Among authors: ertl pf. J Med Chem. 2002 Jan 3;45(1):1-18. doi: 10.1021/jm0102203. J Med Chem. 2002. PMID: 11754575

2

Design and synthesis of pyrrolidine-5,5'-trans-lactams (5-oxo-hexahydropyrrolo[3,2-b]pyrroles) as novel mechanism-based inhibitors of human cytomegalovirus protease. 4. Antiviral activity and plasma stability.

Borthwick AD, Davies DE, Ertl PF, Exall AM, Haley TM, Hart GJ, Jackson DL, Parry NR, Patikis A, Trivedi N, Weingarten GG, Woolven JM. Borthwick AD, et al. Among authors: ertl pf. J Med Chem. 2003 Oct 9;46(21):4428-49. doi: 10.1021/jm030810w. J Med Chem. 2003. PMID: 14521407

3

2-chloro-3-substituted-1,4-naphthoquinone inactivators of human cytomegalovirus protease.

Ertl P, Cooper D, Allen G, Slater MJ. Ertl P, et al. Bioorg Med Chem Lett. 1999 Oct 4;9(19):2863-6. doi: 10.1016/s0960-894x(99)00489-8. Bioorg Med Chem Lett. 1999. PMID: 10522707

4

Technical issues in construction of nucleic acid vaccines.

Ertl PF, Thomsen LL. Ertl PF, et al. Methods. 2003 Nov;31(3):199-206. doi: 10.1016/s1046-2023(03)00134-8. Methods. 2003. PMID: 14511952 Review.

5

High-frequency interferon-gamma-secreting splenocytes specific for murine cytomegalovirus immediate-early-1 (IE-1) peptide 168YPHFMPTNL176 are insufficient to provide complete protection from viral challenge.

Morley PJ, Ertl PF, Sweet C. Morley PJ, et al. Among authors: ertl pf. J Med Virol. 2003 Feb;69(2):240-50. doi: 10.1002/jmv.10272. J Med Virol. 2003. PMID: 12683414

6

Immunisation of Balb/c mice with severely attenuated murine cytomegalovirus mutants induces protective cellular and humoral immunity.

Morley PJ, Ertl P, Sweet C. Morley PJ, et al. J Med Virol. 2002 Jun;67(2):187-99. doi: 10.1002/jmv.2207. J Med Virol. 2002. PMID: 11992579

7

Immune-response profiles induced by human immunodeficiency virus type 1 vaccine DNA, protein or mixed-modality immunization: increased protection from pathogenic simian-human immunodeficiency virus viraemia with protein/DNA combination.

Koopman G, Mortier D, Hofman S, Mathy N, Koutsoukos M, Ertl P, Overend P, van Wely C, Thomsen LL, Wahren B, Voss G, Heeney JL. Koopman G, et al. J Gen Virol. 2008 Feb;89(Pt 2):540-5533. doi: 10.1099/vir.0.83384-0. J Gen Virol. 2008. PMID: 18198386

8

Physical and functional interaction of human cytomegalovirus DNA polymerase and its accessory protein (ICP36) expressed in insect cells.

Ertl PF, Powell KL. Ertl PF, et al. J Virol. 1992 Jul;66(7):4126-33. doi: 10.1128/JVI.66.7.4126-4133.1992. J Virol. 1992. PMID: 1318399 Free PMC article.

9

Characterization of human immunodeficiency virus type 1 reverse transcriptase by using monoclonal antibodies: role of the C terminus in antibody reactivity and enzyme function.

Tisdale M, Ertl P, Larder BA, Purifoy DJ, Darby G, Powell KL. Tisdale M, et al. J Virol. 1988 Oct;62(10):3662-7. doi: 10.1128/JVI.62.10.3662-3667.1988. J Virol. 1988. PMID: 2458486 Free PMC article.

10

Evaluation of immunogenicity and efficacy of combined DNA and adjuvanted protein vaccination in a human immunodeficiency virus type 1/murine leukemia virus pseudotype challenge model.

Rollman E, Mathy N, Bråve A, Boberg A, Kjerrström A, van Wely C, Engström G, Johansson S, Aperia K, Eriksson LE, Benthin R, Ertl P, Heeney J, Hinkula J, Voss G, Wahren B. Rollman E, et al. Vaccine. 2007 Mar 1;25(11):2145-54. doi: 10.1016/j.vaccine.2006.10.057. Epub 2006 Nov 13. Vaccine. 2007. PMID: 17254672

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