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Novel histamine H3 receptor antagonists based on the 4-[(1H-imidazol-4-yl)methyl]piperidine scaffold.
Vaccaro WD, Sher R, Berlin M, Shih NY, Aslanian R, Schwerdt JH, McCormick KD, Piwinski JJ, West RE Jr, Anthes JC, Williams SM, Wu RL, She HS, Rivelli MA, Mutter JC, Corboz MR, Hey JA, Favreau L. Vaccaro WD, et al. Among authors: anthes jc. Bioorg Med Chem Lett. 2006 Jan 15;16(2):395-9. doi: 10.1016/j.bmcl.2005.09.076. Epub 2005 Oct 21. Bioorg Med Chem Lett. 2006. PMID: 16246552
Reduction of CYP450 inhibition in the 4-[(1H-imidazol-4-yl)methyl]piperidine series of histamine H3 receptor antagonists.
Berlin M, Ting PC, Vaccaro WD, Aslanian R, McCormick KD, Lee JF, Albanese MM, Mutahi MW, Piwinski JJ, Shih NY, Duguma L, Solomon DM, Zhou W, Sher R, Favreau L, Bryant M, Korfmacher WA, Nardo C, West RE Jr, Anthes JC, Williams SM, Wu RL, Susan She H, Rivelli MA, Corboz MR, Hey JA. Berlin M, et al. Among authors: anthes jc. Bioorg Med Chem Lett. 2006 Feb 15;16(4):989-94. doi: 10.1016/j.bmcl.2005.10.087. Epub 2005 Nov 15. Bioorg Med Chem Lett. 2006. PMID: 16297617
Dual antagonists of platelet activating factor and histamine. 3. Synthesis, biological activity and conformational implications of substituted N-acyl-bis-arylcycloheptapiperazines.
Piwinski JJ, Wong JK, Green MJ, Kaminski JJ, Colizzo F, Albanese MM, Ganguly AK, Billah MM, Anthes JC, West RE Jr. Piwinski JJ, et al. Among authors: anthes jc. Bioorg Med Chem Lett. 1998 Dec 15;8(24):3469-74. doi: 10.1016/s0960-894x(98)00626-x. Bioorg Med Chem Lett. 1998. PMID: 9934454
The design and synthesis of novel NK1/NK2 dual antagonists.
Reichard GA, Ball ZT, Aslanian R, Anthes JC, Shih NY, Piwinski JJ. Reichard GA, et al. Among authors: anthes jc. Bioorg Med Chem Lett. 2000 Oct 16;10(20):2329-32. doi: 10.1016/s0960-894x(00)00463-7. Bioorg Med Chem Lett. 2000. PMID: 11055349
61 results