Aikawa Y - Search Results

1

Inhibitory effect of T-614 on tumor necrosis factor-alpha induced cytokine production and nuclear factor-kappaB activation in cultured human synovial cells.

Kohno M, Aikawa Y, Tsubouchi Y, Hashiramoto A, Yamada R, Kawahito Y, Inoue K, Kusaka Y, Kondo M, Sano H. Kohno M, et al. Among authors: aikawa y. J Rheumatol. 2001 Dec;28(12):2591-6. J Rheumatol. 2001. PMID: 11764202

2

Inhibitory effects of an anti-rheumatic agent T-614 on immunoglobulin production by cultured B cells and rheumatoid synovial tissues engrafted into SCID mice.

Tanaka K, Yamamoto T, Aikawa Y, Kizawa K, Muramoto K, Matsuno H, Muraguchi A. Tanaka K, et al. Among authors: aikawa y. Rheumatology (Oxford). 2003 Nov;42(11):1365-71. doi: 10.1093/rheumatology/keg381. Epub 2003 Jun 16. Rheumatology (Oxford). 2003. PMID: 12810927

3

Treatment of arthritis with a selective inhibitor of c-Fos/activator protein-1.

Aikawa Y, Morimoto K, Yamamoto T, Chaki H, Hashiramoto A, Narita H, Hirono S, Shiozawa S. Aikawa Y, et al. Nat Biotechnol. 2008 Jul;26(7):817-23. doi: 10.1038/nbt1412. Epub 2008 Jun 29. Nat Biotechnol. 2008. PMID: 18587386

4

An anti-rheumatic agent T-614 inhibits NF-kappaB activation in LPS- and TNF-alpha-stimulated THP-1 cells without interfering with IkappaBalpha degradation.

Aikawa Y, Yamamoto M, Yamamoto T, Morimoto K, Tanaka K. Aikawa Y, et al. Inflamm Res. 2002 Apr;51(4):188-94. doi: 10.1007/pl00000291. Inflamm Res. 2002. PMID: 12058956

5

Pharmacological studies on 3-formylamino-7-methylsulfonylamino-6-phenoxy-4H-1-benzopyran-4-one (T-614), a novel antiinflammatory agent. 4th communication: inhibitory effect on the production of interleukin-1 and interleukin-6.

Tanaka K, Aikawa Y, Kawasaki H, Asaoka K, Inaba T, Yoshida C. Tanaka K, et al. Among authors: aikawa y. J Pharmacobiodyn. 1992 Nov;15(11):649-55. doi: 10.1248/bpb1978.15.649. J Pharmacobiodyn. 1992. PMID: 1289500

6

A new anti-rheumatic drug, T-614, effectively suppresses the development of autoimmune encephalomyelitis.

Aikawa Y, Tanuma N, Shin T, Makino S, Tanaka K, Matsumoto Y. Aikawa Y, et al. J Neuroimmunol. 1998 Aug 14;89(1-2):35-42. doi: 10.1016/s0165-5728(98)00056-3. J Neuroimmunol. 1998. PMID: 9726823

7

Partial purification of gelatinases and effect of anti-inflammatory drugs on the tumor necrosis factor-stimulated production of active gelatinase by granulation tissue in culture.

Nakagawa H, Aikawa Y, Kitagawa H. Nakagawa H, et al. Among authors: aikawa y. J Pharmacobiodyn. 1989 Aug;12(8):448-55. doi: 10.1248/bpb1978.12.448. J Pharmacobiodyn. 1989. PMID: 2559182

8

Competitive PCR quantification of pro- and anti-inflammatory cytokine mRNA in the central nervous system during autoimmune encephalomyelitis.

Tanuma N, Kojima T, Shin T, Aikawa Y, Kohji T, Ishihara Y, Matsumoto Y. Tanuma N, et al. Among authors: aikawa y. J Neuroimmunol. 1997 Mar;73(1-2):197-206. doi: 10.1016/s0165-5728(96)00199-3. J Neuroimmunol. 1997. PMID: 9058777

9

T-614, a novel antirheumatic drug, inhibits both the activity and induction of cyclooxygenase-2 (COX-2) in cultured fibroblasts.

Tanaka K, Kawasaki H, Kurata K, Aikawa Y, Tsukamoto Y, Inaba T. Tanaka K, et al. Among authors: aikawa y. Jpn J Pharmacol. 1995 Apr;67(4):305-14. doi: 10.1254/jjp.67.305. Jpn J Pharmacol. 1995. PMID: 7650864 Free article.

10

A selective inhibition of c-Fos/activator protein-1 as a potential therapeutic target for intervertebral disc degeneration and associated pain.

Makino H, Seki S, Yahara Y, Shiozawa S, Aikawa Y, Motomura H, Nogami M, Watanabe K, Sainoh T, Ito H, Tsumaki N, Kawaguchi Y, Yamazaki M, Kimura T. Makino H, et al. Among authors: aikawa y. Sci Rep. 2017 Dec 5;7(1):16983. doi: 10.1038/s41598-017-17289-y. Sci Rep. 2017. PMID: 29208967 Free PMC article.

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