Lefkowitz RJ - Search Results

1

beta-Arrestin scaffolding of the ERK cascade enhances cytosolic ERK activity but inhibits ERK-mediated transcription following angiotensin AT1a receptor stimulation.

Tohgo A, Pierce KL, Choy EW, Lefkowitz RJ, Luttrell LM. Tohgo A, et al. Among authors: lefkowitz rj. J Biol Chem. 2002 Mar 15;277(11):9429-36. doi: 10.1074/jbc.M106457200. Epub 2002 Jan 2. J Biol Chem. 2002. PMID: 11777902 Free article.

2

Discrete amino acid sequences of the alpha 1-adrenergic receptor determine the selectivity of coupling to phosphatidylinositol hydrolysis.

Cotecchia S, Ostrowski J, Kjelsberg MA, Caron MG, Lefkowitz RJ. Cotecchia S, et al. Among authors: lefkowitz rj. J Biol Chem. 1992 Jan 25;267(3):1633-9. J Biol Chem. 1992. PMID: 1309789 Free article.

3

Sites in the third intracellular loop of the alpha 2A-adrenergic receptor confer short term agonist-promoted desensitization. Evidence for a receptor kinase-mediated mechanism.

Liggett SB, Ostrowski J, Chesnut LC, Kurose H, Raymond JR, Caron MG, Lefkowitz RJ. Liggett SB, et al. Among authors: lefkowitz rj. J Biol Chem. 1992 Mar 5;267(7):4740-6. J Biol Chem. 1992. PMID: 1311318 Free article.

4

Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors.

Pitcher JA, Inglese J, Higgins JB, Arriza JL, Casey PJ, Kim C, Benovic JL, Kwatra MM, Caron MG, Lefkowitz RJ. Pitcher JA, et al. Among authors: lefkowitz rj. Science. 1992 Aug 28;257(5074):1264-7. doi: 10.1126/science.1325672. Science. 1992. PMID: 1325672

5

Constitutive activation of the alpha 1B-adrenergic receptor by all amino acid substitutions at a single site. Evidence for a region which constrains receptor activation.

Kjelsberg MA, Cotecchia S, Ostrowski J, Caron MG, Lefkowitz RJ. Kjelsberg MA, et al. Among authors: lefkowitz rj. J Biol Chem. 1992 Jan 25;267(3):1430-3. J Biol Chem. 1992. PMID: 1346134 Free article.

6

Desensitization of the isolated beta 2-adrenergic receptor by beta-adrenergic receptor kinase, cAMP-dependent protein kinase, and protein kinase C occurs via distinct molecular mechanisms.

Pitcher J, Lohse MJ, Codina J, Caron MG, Lefkowitz RJ. Pitcher J, et al. Among authors: lefkowitz rj. Biochemistry. 1992 Mar 31;31(12):3193-7. doi: 10.1021/bi00127a021. Biochemistry. 1992. PMID: 1348186

7

Receptor-specific desensitization with purified proteins. Kinase dependence and receptor specificity of beta-arrestin and arrestin in the beta 2-adrenergic receptor and rhodopsin systems.

Lohse MJ, Andexinger S, Pitcher J, Trukawinski S, Codina J, Faure JP, Caron MG, Lefkowitz RJ. Lohse MJ, et al. Among authors: lefkowitz rj. J Biol Chem. 1992 Apr 25;267(12):8558-64. J Biol Chem. 1992. PMID: 1349018 Free article.

8

The G-protein-coupled receptor kinases beta ARK1 and beta ARK2 are widely distributed at synapses in rat brain.

Arriza JL, Dawson TM, Simerly RB, Martin LJ, Caron MG, Snyder SH, Lefkowitz RJ. Arriza JL, et al. Among authors: lefkowitz rj. J Neurosci. 1992 Oct;12(10):4045-55. doi: 10.1523/JNEUROSCI.12-10-04045.1992. J Neurosci. 1992. PMID: 1403099 Free PMC article.

9

Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family.

Attramadal H, Arriza JL, Aoki C, Dawson TM, Codina J, Kwatra MM, Snyder SH, Caron MG, Lefkowitz RJ. Attramadal H, et al. Among authors: lefkowitz rj. J Biol Chem. 1992 Sep 5;267(25):17882-90. J Biol Chem. 1992. PMID: 1517224 Free article.

10

Comparative rates of desensitization of beta-adrenergic receptors by the beta-adrenergic receptor kinase and the cyclic AMP-dependent protein kinase.

Roth NS, Campbell PT, Caron MG, Lefkowitz RJ, Lohse MJ. Roth NS, et al. Among authors: lefkowitz rj. Proc Natl Acad Sci U S A. 1991 Jul 15;88(14):6201-4. doi: 10.1073/pnas.88.14.6201. Proc Natl Acad Sci U S A. 1991. PMID: 1648731 Free PMC article.

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