Moores K - Search Results

1

Fractalkine is expressed by smooth muscle cells in response to IFN-gamma and TNF-alpha and is modulated by metalloproteinase activity.

Ludwig A, Berkhout T, Moores K, Groot P, Chapman G. Ludwig A, et al. Among authors: moores k. J Immunol. 2002 Jan 15;168(2):604-12. doi: 10.4049/jimmunol.168.2.604. J Immunol. 2002. PMID: 11777952

2

Identification of a truncated form of the CC chemokine CK beta-8 demonstrating greatly enhanced biological activity.

Macphee CH, Appelbaum ER, Johanson K, Moores KE, Imburgia CS, Fornwald J, Berkhout T, Brawner M, Groot PH, O'Donnell K, O'Shannessy D, Scott G, White JR. Macphee CH, et al. Among authors: moores ke. J Immunol. 1998 Dec 1;161(11):6273-9. J Immunol. 1998. PMID: 9834116

3

Fractalkine cleavage from neuronal membranes represents an acute event in the inflammatory response to excitotoxic brain damage.

Chapman GA, Moores K, Harrison D, Campbell CA, Stewart BR, Strijbos PJ. Chapman GA, et al. Among authors: moores k. J Neurosci. 2000 Aug 1;20(15):RC87. doi: 10.1523/JNEUROSCI.20-15-j0004.2000. J Neurosci. 2000. PMID: 10899174 Free PMC article.

4

Selective binding of the truncated form of the chemokine CKbeta8 (25-99) to CC chemokine receptor 1(CCR1).

Berkhout TA, Gohil J, Gonzalez P, Nicols CL, Moores KE, Macphee CH, White JR, Groot PH. Berkhout TA, et al. Among authors: moores ke. Biochem Pharmacol. 2000 Mar 1;59(5):591-6. doi: 10.1016/s0006-2952(99)00354-8. Biochem Pharmacol. 2000. PMID: 10660125

5

The role of fractalkine in the recruitment of monocytes to the endothelium.

Chapman GA, Moores KE, Gohil J, Berkhout TA, Patel L, Green P, Macphee CH, Stewart BR. Chapman GA, et al. Among authors: moores ke. Eur J Pharmacol. 2000 Mar 31;392(3):189-95. doi: 10.1016/s0014-2999(00)00117-5. Eur J Pharmacol. 2000. PMID: 10762673

6

CCR2: characterization of the antagonist binding site from a combined receptor modeling/mutagenesis approach.

Berkhout TA, Blaney FE, Bridges AM, Cooper DG, Forbes IT, Gribble AD, Groot PH, Hardy A, Ife RJ, Kaur R, Moores KE, Shillito H, Willetts J, Witherington J. Berkhout TA, et al. J Med Chem. 2003 Sep 11;46(19):4070-86. doi: 10.1021/jm030862l. J Med Chem. 2003. PMID: 12954060

7

Cloning, in vitro expression, and functional characterization of a novel human CC chemokine of the monocyte chemotactic protein (MCP) family (MCP-4) that binds and signals through the CC chemokine receptor 2B.

Berkhout TA, Sarau HM, Moores K, White JR, Elshourbagy N, Appelbaum E, Reape RJ, Brawner M, Makwana J, Foley JJ, Schmidt DB, Imburgia C, McNulty D, Matthews J, O'Donnell K, O'Shannessy D, Scott M, Groot PH, Macphee C. Berkhout TA, et al. Among authors: moores k. J Biol Chem. 1997 Jun 27;272(26):16404-13. doi: 10.1074/jbc.272.26.16404. J Biol Chem. 1997. PMID: 9195948 Free article.

8

CCR2B receptor antagonists: conversion of a weak HTS hit to a potent lead compound.

Forbes IT, Cooper DG, Dodds EK, Hickey DM, Ife RJ, Meeson M, Stockley M, Berkhout TA, Gohil J, Groot PH, Moores K. Forbes IT, et al. Among authors: moores k. Bioorg Med Chem Lett. 2000 Aug 21;10(16):1803-6. doi: 10.1016/s0960-894x(00)00347-4. Bioorg Med Chem Lett. 2000. PMID: 10969972

9

PPARgamma is not a critical mediator of primary monocyte differentiation or foam cell formation.

Patel L, Charlton SJ, Marshall IC, Moore GB, Coxon P, Moores K, Clapham JC, Newman SJ, Smith SA, Macphee CH. Patel L, et al. Among authors: moores k. Biochem Biophys Res Commun. 2002 Jan 18;290(2):707-12. doi: 10.1006/bbrc.2001.6263. Biochem Biophys Res Commun. 2002. PMID: 11785957

10

Sema7A is a potent monocyte stimulator.

Holmes S, Downs AM, Fosberry A, Hayes PD, Michalovich D, Murdoch P, Moores K, Fox J, Deen K, Pettman G, Wattam T, Lewis C. Holmes S, et al. Among authors: moores k. Scand J Immunol. 2002 Sep;56(3):270-5. doi: 10.1046/j.1365-3083.2002.01129.x. Scand J Immunol. 2002. PMID: 12193228 Free article.

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