Rose DM - Search Results

1

Increased filamin binding to beta-integrin cytoplasmic domains inhibits cell migration.

Calderwood DA, Huttenlocher A, Kiosses WB, Rose DM, Woodside DG, Schwartz MA, Ginsberg MH. Calderwood DA, et al. Among authors: rose dm. Nat Cell Biol. 2001 Dec;3(12):1060-8. doi: 10.1038/ncb1201-1060. Nat Cell Biol. 2001. PMID: 11781567

2

A fragment of paxillin binds the alpha 4 integrin cytoplasmic domain (tail) and selectively inhibits alpha 4-mediated cell migration.

Liu S, Kiosses WB, Rose DM, Slepak M, Salgia R, Griffin JD, Turner CE, Schwartz MA, Ginsberg MH. Liu S, et al. Among authors: rose dm. J Biol Chem. 2002 Jun 7;277(23):20887-94. doi: 10.1074/jbc.M110928200. Epub 2002 Mar 27. J Biol Chem. 2002. PMID: 11919182 Free article.

3

Paxillin binding to the alpha 4 integrin subunit stimulates LFA-1 (integrin alpha L beta 2)-dependent T cell migration by augmenting the activation of focal adhesion kinase/proline-rich tyrosine kinase-2.

Rose DM, Liu S, Woodside DG, Han J, Schlaepfer DD, Ginsberg MH. Rose DM, et al. J Immunol. 2003 Jun 15;170(12):5912-8. doi: 10.4049/jimmunol.170.12.5912. J Immunol. 2003. PMID: 12794117

4

Integrin alpha 4 beta 1-dependent T cell migration requires both phosphorylation and dephosphorylation of the alpha 4 cytoplasmic domain to regulate the reversible binding of paxillin.

Han J, Rose DM, Woodside DG, Goldfinger LE, Ginsberg MH. Han J, et al. Among authors: rose dm. J Biol Chem. 2003 Sep 12;278(37):34845-53. doi: 10.1074/jbc.M304691200. Epub 2003 Jun 30. J Biol Chem. 2003. PMID: 12837751 Free article.

5

Binding of paxillin to alpha4 integrins modifies integrin-dependent biological responses.

Liu S, Thomas SM, Woodside DG, Rose DM, Kiosses WB, Pfaff M, Ginsberg MH. Liu S, et al. Among authors: rose dm. Nature. 1999 Dec 9;402(6762):676-81. doi: 10.1038/45264. Nature. 1999. PMID: 10604475

6

The affinity of integrin alpha(4)beta(1) governs lymphocyte migration.

Rose DM, Grabovsky V, Alon R, Ginsberg MH. Rose DM, et al. J Immunol. 2001 Sep 1;167(5):2824-30. doi: 10.4049/jimmunol.167.5.2824. J Immunol. 2001. PMID: 11509628

7

Phosphorylation of the integrin alpha 4 cytoplasmic domain regulates paxillin binding.

Han J, Liu S, Rose DM, Schlaepfer DD, McDonald H, Ginsberg MH. Han J, et al. Among authors: rose dm. J Biol Chem. 2001 Nov 2;276(44):40903-9. doi: 10.1074/jbc.M102665200. Epub 2001 Aug 30. J Biol Chem. 2001. PMID: 11533025 Free article.

8

Integrin modulation and signaling in leukocyte adhesion and migration.

Rose DM, Alon R, Ginsberg MH. Rose DM, et al. Immunol Rev. 2007 Aug;218:126-34. doi: 10.1111/j.1600-065X.2007.00536.x. Immunol Rev. 2007. PMID: 17624949 Review.

9

Integrin-associated proteins as potential therapeutic targets.

Cantor JM, Ginsberg MH, Rose DM. Cantor JM, et al. Among authors: rose dm. Immunol Rev. 2008 Jun;223:236-51. doi: 10.1111/j.1600-065X.2008.00640.x. Immunol Rev. 2008. PMID: 18613840 Review.

10

A small molecule that inhibits the interaction of paxillin and alpha 4 integrin inhibits accumulation of mononuclear leukocytes at a site of inflammation.

Kummer C, Petrich BG, Rose DM, Ginsberg MH. Kummer C, et al. Among authors: rose dm. J Biol Chem. 2010 Mar 26;285(13):9462-9469. doi: 10.1074/jbc.M109.066993. Epub 2010 Jan 22. J Biol Chem. 2010. PMID: 20097761 Free PMC article.

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