Spenkelink A - Search Results

1

Detection of estrogenic potency in wastewater and surface water with three in vitro bioassays.

Murk AJ, Legler J, van Lipzig MM, Meerman JH, Belfroid AC, Spenkelink A, van der Burg B, Rijs GB, Vethaak D. Murk AJ, et al. Among authors: spenkelink a. Environ Toxicol Chem. 2002 Jan;21(1):16-23. Environ Toxicol Chem. 2002. PMID: 11808534

2

In vitro biomonitoring in polar extracts of solid phase matrices reveals the presence of unknown compounds with estrogenic activity.

Legler J, Leonards P, Spenkelink A, Murk AJ. Legler J, et al. Among authors: spenkelink a. Ecotoxicology. 2003 Feb-Aug;12(1-4):239-49. doi: 10.1023/a:1022558911779. Ecotoxicology. 2003. PMID: 12739871

3

Delayed effects of pre- and early-life time exposure to polychlorinated biphenyls on tadpoles of two amphibian species (Xenopus laevis and Rana temporaria).

Gutleb AC, Appelman J, Bronkhorst MC, van den Berg JH, Spenkelink A, Brouwer A, Murk AJ. Gutleb AC, et al. Among authors: spenkelink a. Environ Toxicol Pharmacol. 1999 Dec;8(1):1-14. doi: 10.1016/s1382-6689(99)00023-x. Environ Toxicol Pharmacol. 1999. PMID: 21781936

4

Transport and metabolism of glutathione conjugates of menadione and ethacrynic acid in confluent monolayers of rat renal proximal tubular cells.

Haenen HE, Spenkelink A, Teunissen C, Temmink JH, Koeman JH, van Bladeren PJ. Haenen HE, et al. Among authors: spenkelink a. Toxicology. 1996 Aug 16;112(2):117-30. doi: 10.1016/0300-483x(96)82323-7. Toxicology. 1996. PMID: 8814341

5

Inhibition of binding of thyroxin to transthyretin by outdoor and indoor airborne particulate matter and effects on thyroid hormone and vitamin A metabolism in rats.

Heussen GA, Hikspoors ML, Spenkelink A, Brouwer A, Koeman JH. Heussen GA, et al. Among authors: spenkelink a. Arch Environ Contam Toxicol. 1992 Jul;23(1):6-12. doi: 10.1007/BF00225989. Arch Environ Contam Toxicol. 1992. PMID: 1637200

6

Genotoxic effects in the Eastern mudminnow (Umbra pygmaea L.) after exposure to Rhine water, as assessed by use of the SCE and Comet assays: a comparison between 1978 and 2005.

Alink GM, Quik JT, Penders EJ, Spenkelink A, Rotteveel SG, Maas JL, Hoogenboezem W. Alink GM, et al. Among authors: spenkelink a. Mutat Res. 2007 Jul 28;631(2):93-100. doi: 10.1016/j.mrgentox.2007.03.011. Epub 2007 Apr 29. Mutat Res. 2007. PMID: 17561437

7

An in vitromodel to quantify interspecies differences in kinetics for intestinal microbial bioactivation and detoxification of zearalenone.

Mendez-Catala DM, Spenkelink A, Rietjens IMCM, Beekmann K. Mendez-Catala DM, et al. Among authors: spenkelink a. Toxicol Rep. 2020 Jul 24;7:938-946. doi: 10.1016/j.toxrep.2020.07.010. eCollection 2020. Toxicol Rep. 2020. PMID: 32793423 Free PMC article.

8

Identification of nevadensin as an important herb-based constituent inhibiting estragole bioactivation and physiology-based biokinetic modeling of its possible in vivo effect.

Alhusainy W, Paini A, Punt A, Louisse J, Spenkelink A, Vervoort J, Delatour T, Scholz G, Schilter B, Adams T, van Bladeren PJ, Rietjens IM. Alhusainy W, et al. Among authors: spenkelink a. Toxicol Appl Pharmacol. 2010 Jun 1;245(2):179-90. doi: 10.1016/j.taap.2010.02.017. Epub 2010 Mar 11. Toxicol Appl Pharmacol. 2010. PMID: 20226806

9

Genotoxic effects in the Eastern mudminnow (Umbra pygmaea) after prolonged exposure to River Rhine water, as assessed by use of the in vivo SCE and Comet assays.

Penders EJ, Spenkelink A, Hoogenboezem W, Rotteveel SG, Maas JL, Alink GM. Penders EJ, et al. Among authors: spenkelink a. Environ Mol Mutagen. 2012 May;53(4):304-10. doi: 10.1002/em.21687. Epub 2012 Mar 19. Environ Mol Mutagen. 2012. PMID: 22430935

10

A physiologically based in silico model for trans-2-hexenal detoxification and DNA adduct formation in human including interindividual variation indicates efficient detoxification and a negligible genotoxicity risk.

Kiwamoto R, Spenkelink A, Rietjens IM, Punt A. Kiwamoto R, et al. Among authors: spenkelink a. Arch Toxicol. 2013 Sep;87(9):1725-37. doi: 10.1007/s00204-013-1091-8. Epub 2013 Jul 18. Arch Toxicol. 2013. PMID: 23864024

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