Brand CL - Search Results

1

Novel tricyclic-alpha-alkyloxyphenylpropionic acids: dual PPARalpha/gamma agonists with hypolipidemic and antidiabetic activity.

Sauerberg P, Pettersson I, Jeppesen L, Bury PS, Mogensen JP, Wassermann K, Brand CL, Sturis J, Wöldike HF, Fleckner J, Andersen AS, Mortensen SB, Svensson LA, Rasmussen HB, Lehmann SV, Polivka Z, Sindelar K, Panajotova V, Ynddal L, Wulff EM. Sauerberg P, et al. Among authors: brand cl. J Med Chem. 2002 Feb 14;45(4):789-804. doi: 10.1021/jm010964g. J Med Chem. 2002. PMID: 11831892

2

Dual PPARalpha /gamma activation provides enhanced improvement of insulin sensitivity and glycemic control in ZDF rats.

Brand CL, Sturis J, Gotfredsen CF, Fleckner J, Fledelius C, Hansen BF, Andersen B, Ye JM, Sauerberg P, Wassermann K. Brand CL, et al. Am J Physiol Endocrinol Metab. 2003 Apr;284(4):E841-54. doi: 10.1152/ajpendo.00348.2002. Epub 2002 Dec 10. Am J Physiol Endocrinol Metab. 2003. PMID: 12475752 Free article.

3

Optimization of alkylidene hydrazide based human glucagon receptor antagonists. Discovery of the highly potent and orally available 3-cyano-4-hydroxybenzoic acid [1-(2,3,5,6-tetramethylbenzyl)-1H-indol-4-ylmethylene]hydrazide.

Madsen P, Ling A, Plewe M, Sams CK, Knudsen LB, Sidelmann UG, Ynddal L, Brand CL, Andersen B, Murphy D, Teng M, Truesdale L, Kiel D, May J, Kuki A, Shi S, Johnson MD, Teston KA, Feng J, Lakis J, Anderes K, Gregor V, Lau J. Madsen P, et al. Among authors: brand cl. J Med Chem. 2002 Dec 19;45(26):5755-75. doi: 10.1021/jm0208572. J Med Chem. 2002. PMID: 12477359

4

New beta-alanine derivatives are orally available glucagon receptor antagonists.

Lau J, Behrens C, Sidelmann UG, Knudsen LB, Lundt B, Sams C, Ynddal L, Brand CL, Pridal L, Ling A, Kiel D, Plewe M, Shi S, Madsen P. Lau J, et al. Among authors: brand cl. J Med Chem. 2007 Jan 11;50(1):113-28. doi: 10.1021/jm058026u. J Med Chem. 2007. PMID: 17201415

5

Human glucagon receptor antagonists with thiazole cores. A novel series with superior pharmacokinetic properties.

Madsen P, Kodra JT, Behrens C, Nishimura E, Jeppesen CB, Pridal L, Andersen B, Knudsen LB, Valcarce-Aspegren C, Guldbrandt M, Christensen IT, Jørgensen AS, Ynddal L, Brand CL, Bagger MA, Lau J. Madsen P, et al. Among authors: brand cl. J Med Chem. 2009 May 14;52(9):2989-3000. doi: 10.1021/jm8016249. J Med Chem. 2009. PMID: 19385613

6

Synergistic effect of the human GLP-1 analogue liraglutide and a dual PPARalpha/gamma agonist on glycaemic control in Zucker diabetic fatty rats.

Brand CL, Galsgaard ED, Tornehave D, Rømer J, Gotfredsen CF, Wassermann K, Knudsen LB, Vølund A, Sturis J. Brand CL, et al. Diabetes Obes Metab. 2009 Aug;11(8):795-803. doi: 10.1111/j.1463-1326.2009.01049.x. Epub 2009 Jun 10. Diabetes Obes Metab. 2009. PMID: 19519868

7

NN414, a SUR1/Kir6.2-selective potassium channel opener, reduces blood glucose and improves glucose tolerance in the VDF Zucker rat.

Carr RD, Brand CL, Bodvarsdottir TB, Hansen JB, Sturis J. Carr RD, et al. Among authors: brand cl. Diabetes. 2003 Oct;52(10):2513-8. doi: 10.2337/diabetes.52.10.2513. Diabetes. 2003. PMID: 14514634

8

The dual PPARalpha/gamma agonist, ragaglitazar, improves insulin sensitivity and metabolic profile equally with pioglitazone in diabetic and dietary obese ZDF rats.

Pickavance LC, Brand CL, Wassermann K, Wilding JP. Pickavance LC, et al. Among authors: brand cl. Br J Pharmacol. 2005 Feb;144(3):308-16. doi: 10.1038/sj.bjp.0706041. Br J Pharmacol. 2005. PMID: 15655531 Free PMC article.

9

GLP-1 derivative liraglutide in rats with beta-cell deficiencies: influence of metabolic state on beta-cell mass dynamics.

Sturis J, Gotfredsen CF, Rømer J, Rolin B, Ribel U, Brand CL, Wilken M, Wassermann K, Deacon CF, Carr RD, Knudsen LB. Sturis J, et al. Among authors: brand cl. Br J Pharmacol. 2003 Sep;140(1):123-32. doi: 10.1038/sj.bjp.0705397. Epub 2003 Jul 29. Br J Pharmacol. 2003. PMID: 12967942 Free PMC article.

10

Sensory nerve inactivation by resiniferatoxin improves insulin sensitivity in male obese Zucker rats.

Moesgaard SG, Brand CL, Sturis J, Ahrén B, Wilken M, Fleckner J, Carr RD, Svendsen O, Hansen AJ, Gram DX. Moesgaard SG, et al. Among authors: brand cl. Am J Physiol Endocrinol Metab. 2005 Jun;288(6):E1137-45. doi: 10.1152/ajpendo.00356.2004. Am J Physiol Endocrinol Metab. 2005. PMID: 15883192 Free article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

138 results

Search Page

Filters