Schofield CJ - Search Results

1

Enzymatic synthesis of monocyclic beta-lactams.

Sleeman MC, MacKinnon CH, Hewitson KS, Schofield CJ. Sleeman MC, et al. Among authors: schofield cj. Bioorg Med Chem Lett. 2002 Feb 25;12(4):597-9. doi: 10.1016/s0960-894x(01)00806-x. Bioorg Med Chem Lett. 2002. PMID: 11844680

2

delta-L-(alpha-aminoadipoyl)-L-cysteinyl-D-valine synthetase: the order of peptide bond formation and timing of the epimerisation reaction.

Shiau CY, Baldwin JE, Byford MF, Sobey WJ, Schofield CJ. Shiau CY, et al. Among authors: schofield cj. FEBS Lett. 1995 Jan 16;358(1):97-100. doi: 10.1016/0014-5793(94)01320-z. FEBS Lett. 1995. PMID: 7821439 Free article.

3

Inhibition of elastase by N-sulfonylaryl beta-lactams: anatomy of a stable acyl-enzyme complex.

Wilmouth RC, Westwood NJ, Anderson K, Brownlee W, Claridge TD, Clifton IJ, Pritchard GJ, Aplin RT, Schofield CJ. Wilmouth RC, et al. Among authors: schofield cj. Biochemistry. 1998 Dec 15;37(50):17506-13. doi: 10.1021/bi9816249. Biochemistry. 1998. PMID: 9860865

4

Mechanistic insights into the inhibition of serine proteases by monocyclic lactams.

Wilmouth RC, Kassamally S, Westwood NJ, Sheppard RJ, Claridge TD, Aplin RT, Wright PA, Pritchard GJ, Schofield CJ. Wilmouth RC, et al. Among authors: schofield cj. Biochemistry. 1999 Jun 22;38(25):7989-98. doi: 10.1021/bi990098y. Biochemistry. 1999. PMID: 10387042

5

Mass spectrometry reveals elastase inhibitors from the reactive centre loop of alpha1-antitrypsin.

Wright PA, Rostom AA, Robinson CV, Schofield CJ. Wright PA, et al. Among authors: schofield cj. Bioorg Med Chem Lett. 2000 Jun 5;10(11):1219-21. doi: 10.1016/s0960-894x(00)00194-3. Bioorg Med Chem Lett. 2000. PMID: 10866385

6

Studies on phytanoyl-CoA 2-hydroxylase and synthesis of phytanoyl-coenzyme A.

Kershaw NJ, Mukherji M, MacKinnon CH, Claridge TD, Odell B, Wierzbicki AS, Lloyd MD, Schofield CJ. Kershaw NJ, et al. Among authors: schofield cj. Bioorg Med Chem Lett. 2001 Sep 17;11(18):2545-8. doi: 10.1016/s0960-894x(01)00494-2. Bioorg Med Chem Lett. 2001. PMID: 11549466

7

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation.

Epstein AC, Gleadle JM, McNeill LA, Hewitson KS, O'Rourke J, Mole DR, Mukherji M, Metzen E, Wilson MI, Dhanda A, Tian YM, Masson N, Hamilton DL, Jaakkola P, Barstead R, Hodgkin J, Maxwell PH, Pugh CW, Schofield CJ, Ratcliffe PJ. Epstein AC, et al. Among authors: schofield cj. Cell. 2001 Oct 5;107(1):43-54. doi: 10.1016/s0092-8674(01)00507-4. Cell. 2001. PMID: 11595184 Free article.

8

ORF6 from the clavulanic acid gene cluster of Streptomyces clavuligerus has ornithine acetyltransferase activity.

Kershaw NJ, McNaughton HJ, Hewitson KS, Hernández H, Griffin J, Hughes C, Greaves P, Barton B, Robinson CV, Schofield CJ. Kershaw NJ, et al. Among authors: schofield cj. Eur J Biochem. 2002 Apr;269(8):2052-9. doi: 10.1046/j.1432-1033.2002.02853.x. Eur J Biochem. 2002. PMID: 11985581 Free article.

9

Oligomeric structure of proclavaminic acid amidino hydrolase: evolution of a hydrolytic enzyme in clavulanic acid biosynthesis.

Elkins JM, Clifton IJ, Hernández H, Doan LX, Robinson CV, Schofield CJ, Hewitson KS. Elkins JM, et al. Among authors: schofield cj. Biochem J. 2002 Sep 1;366(Pt 2):423-34. doi: 10.1042/BJ20020125. Biochem J. 2002. PMID: 12020346 Free PMC article.

10

The use of dioxygen by HIF prolyl hydroxylase (PHD1).

McNeill LA, Hewitson KS, Gleadle JM, Horsfall LE, Oldham NJ, Maxwell PH, Pugh CW, Ratcliffe PJ, Schofield CJ. McNeill LA, et al. Among authors: schofield cj. Bioorg Med Chem Lett. 2002 Jun 17;12(12):1547-50. doi: 10.1016/s0960-894x(02)00219-6. Bioorg Med Chem Lett. 2002. PMID: 12039559

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