Strickland CL - Search Results

1

Synthesis of 5,6-dihydro-11H-benzo[5,6]-cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidine-N-cyanoguanidine derivatives as inhibitors of ras farnesyl protein transferase.

Cooper AB, Strickland CL, Wang J, Desai J, Kirschmeier P, Patton R, Bishop WR, Weber PC, Girijavallabhan V. Cooper AB, et al. Among authors: strickland cl. Bioorg Med Chem Lett. 2002 Feb 25;12(4):601-5. doi: 10.1016/s0960-894x(01)00826-5. Bioorg Med Chem Lett. 2002. PMID: 11844681

2

Exploring the role of bromine at C(10) of (+)-4-[2-[4-(8-chloro-3,10-dibromo- 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11(R)-yl)-1-piperidinyl]-2- oxoethyl]-1-piperidinecarboxamide (Sch-66336): the discovery of indolocycloheptapyridine inhibitors of farnesyl protein transferase.

Taveras AG, Aki C, Chao J, Doll RJ, Lalwani T, Girijavallabhan V, Strickland CL, Windsor WT, Weber P, Hollinger F, Snow M, Patton R, Kirschmeier P, James L, Liu M, Nomeir A. Taveras AG, et al. Among authors: strickland cl. J Med Chem. 2002 Aug 29;45(18):3854-64. doi: 10.1021/jm010463v. J Med Chem. 2002. PMID: 12190309

3

Trihalobenzocycloheptapyridine analogues of Sch 66336 as potent inhibitors of farnesyl protein transferase.

Njoroge FG, Vibulbhan B, Pinto P, Strickland CL, Bishop WR, Kirschmeir P, Girijavallabhan V, Ganguly AK. Njoroge FG, et al. Among authors: strickland cl. Bioorg Med Chem. 2003 Jan 2;11(1):139-43. doi: 10.1016/s0968-0896(02)00308-5. Bioorg Med Chem. 2003. PMID: 12467716

4

Tricyclic farnesyl protein transferase inhibitors: crystallographic and calorimetric studies of structure-activity relationships.

Strickland CL, Weber PC, Windsor WT, Wu Z, Le HV, Albanese MM, Alvarez CS, Cesarz D, del Rosario J, Deskus J, Mallams AK, Njoroge FG, Piwinski JJ, Remiszewski S, Rossman RR, Taveras AG, Vibulbhan B, Doll RJ, Girijavallabhan VM, Ganguly AK. Strickland CL, et al. J Med Chem. 1999 Jun 17;42(12):2125-35. doi: 10.1021/jm990030g. J Med Chem. 1999. PMID: 10377218

5

Farnesyl protein transferase: a review of structural studies.

Strickland CL, Weber PC. Strickland CL, et al. Curr Opin Drug Discov Devel. 1999 Sep;2(5):475-83. Curr Opin Drug Discov Devel. 1999. PMID: 19649974

6

Guiding farnesyltransferase inhibitors from an ECLiPS library to the catalytic zinc.

Huang CY, Stauffer TM, Strickland CL, Reader JC, Huang H, Li G, Cooper AB, Doll RJ, Ganguly AK, Baldwin JJ, Rokosz LL. Huang CY, et al. Among authors: strickland cl. Bioorg Med Chem Lett. 2006 Feb;16(3):507-11. doi: 10.1016/j.bmcl.2005.10.070. Epub 2005 Nov 10. Bioorg Med Chem Lett. 2006. PMID: 16289818

7

Crystal structure of farnesyl protein transferase complexed with a CaaX peptide and farnesyl diphosphate analogue.

Strickland CL, Windsor WT, Syto R, Wang L, Bond R, Wu Z, Schwartz J, Le HV, Beese LS, Weber PC. Strickland CL, et al. Biochemistry. 1998 Nov 24;37(47):16601-11. doi: 10.1021/bi981197z. Biochemistry. 1998. PMID: 9843427

8

Biochemical and crystallographic characterization of homologous non-peptidic thrombin inhibitors having alternate binding modes.

Strickland CL, Fevig JM, Galemmo RA Jr, Wells BL, Kettner CA, Weber PC. Strickland CL, et al. Acta Crystallogr D Biol Crystallogr. 1998 Nov 1;54(Pt 6 Pt 2):1207-15. doi: 10.1107/s0907444997019744. Acta Crystallogr D Biol Crystallogr. 1998. PMID: 10089499

9

High-level expression, purification, kinetic characterization and crystallization of protein farnesyltransferase beta-subunit C-terminal mutants.

Wu Z, Demma M, Strickland CL, Syto R, Le HV, Windsor WT, Weber PC. Wu Z, et al. Among authors: strickland cl. Protein Eng. 1999 Apr;12(4):341-8. doi: 10.1093/protein/12.4.341. Protein Eng. 1999. PMID: 10325405

10

Synthesis of farnesyl diphosphate analogues containing ether-linked photoactive benzophenones and their application in studies of protein prenyltransferases.

Turek TC, Gaon I, Distefano MD, Strickland CL. Turek TC, et al. Among authors: strickland cl. J Org Chem. 2001 May 18;66(10):3253-64. doi: 10.1021/jo991130x. J Org Chem. 2001. PMID: 11348105

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