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14 results

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Page 1
The discovery of acylated beta-amino acids as potent and orally bioavailable VLA-4 antagonists.
Lin LS, Kopka IE, Mumford RA, Magriotis PA, Lanza T Jr, Durette PL, Kamenecka T, Young DN, de Laszlo SE, McCauley E, Riper GV, Kidambi U, Egger LA, Tong X, Lyons K, Vincent S, Stearns R, Colletti A, Teffera Y, Fenyk-Melody J, Schmidt JA, MacCoss M, Hagmann WK. Lin LS, et al. Among authors: kidambi u. Bioorg Med Chem Lett. 2002 Feb 25;12(4):611-4. doi: 10.1016/s0960-894x(01)00818-6. Bioorg Med Chem Lett. 2002. PMID: 11844683
Specific and dual antagonists of alpha(4)beta(1) and alpha(4)beta(7) integrins.
Lin LS, Lanza T Jr, McCauley E, Van Riper G, Kidambi U, Cao J, Egger LA, Mumford RA, Schmidt JA, MacCoss M, Hagmann WK. Lin LS, et al. Among authors: kidambi u. Bioorg Med Chem Lett. 2002 Jan 21;12(2):133-6. doi: 10.1016/s0960-894x(01)00705-3. Bioorg Med Chem Lett. 2002. PMID: 11755338
Substituted N-(3,5-dichlorobenzenesulfonyl)-L-prolyl-phenylalanine analogues as potent VLA-4 antagonists.
Kopka IE, Young DN, Lin LS, Mumford RA, Magriotis PA, MacCoss M, Mills SG, Van Riper G, McCauley E, Egger LE, Kidambi U, Schmidt JA, Lyons K, Stearns R, Vincent S, Colletti A, Wang Z, Tong S, Wang J, Zheng S, Owens K, Levorse D, Hagmann WK. Kopka IE, et al. Among authors: kidambi u. Bioorg Med Chem Lett. 2002 Feb 25;12(4):637-40. doi: 10.1016/s0960-894x(01)00821-6. Bioorg Med Chem Lett. 2002. PMID: 11844689
N-Tetrahydrofuroyl-(L)-phenylalanine derivatives as potent VLA-4 antagonists.
Yang GX, Chang LL, Truong Q, Doherty GA, Magriotis PA, de Laszlo SE, Li B, MacCoss M, Kidambi U, Egger LA, McCauley E, Van Riper G, Mumford RA, Schmidt JA, Hagmann WK. Yang GX, et al. Among authors: kidambi u. Bioorg Med Chem Lett. 2002 Jun 3;12(11):1497-500. doi: 10.1016/s0960-894x(02)00210-x. Bioorg Med Chem Lett. 2002. PMID: 12031328
N-aryl-prolyl-dipeptides as potent antagonists of VLA-4.
Kamenecka TM, Lanza T Jr, de Laszlo SE, Li B, McCauley ED, Van Riper G, Egger LA, Kidambi U, Mumford RA, Tong S, MacCoss M, Schmidt JA, Hagmann WK. Kamenecka TM, et al. Among authors: kidambi u. Bioorg Med Chem Lett. 2002 Aug 19;12(16):2205-8. doi: 10.1016/s0960-894x(02)00356-6. Bioorg Med Chem Lett. 2002. PMID: 12127538
Substituted 3-amino biaryl propionic acids as potent VLA-4 antagonists.
Kopka IE, Lin LS, Mumford RA, Lanza T Jr, Magriotis PA, Young D, DeLaszlo SE, MacCoss M, Mills SG, Van Riper G, McCauley E, Lyons K, Vincent S, Egger LA, Kidambi U, Stearns R, Colletti A, Teffera Y, Tong S, Owens K, Levorse D, Schmidt JA, Hagmann WK. Kopka IE, et al. Among authors: kidambi u. Bioorg Med Chem Lett. 2002 Sep 2;12(17):2415-8. doi: 10.1016/s0960-894x(02)00460-2. Bioorg Med Chem Lett. 2002. PMID: 12161146
Amidines as amide bond replacements in VLA-4 antagonists.
Kamenecka TM, Park YJ, Lin LS, de Laszlo S, McCauley ED, Van Riper G, Egger L, Kidambi U, Mumford RA, Tong S, Tang W, Colletti A, Teffera Y, Stearns R, MacCoss M, Schmidt JA, Hagmann WK. Kamenecka TM, et al. Among authors: kidambi u. Bioorg Med Chem Lett. 2004 May 3;14(9):2323-6. doi: 10.1016/j.bmcl.2004.01.100. Bioorg Med Chem Lett. 2004. PMID: 15081033
14 results