Ashworth A - Search Results

1

Disruption of Brca2 increases the spontaneous mutation rate in vivo: synergism with ionizing radiation.

Tutt AN, van Oostrom CT, Ross GM, van Steeg H, Ashworth A. Tutt AN, et al. Among authors: ashworth a. EMBO Rep. 2002 Mar;3(3):255-60. doi: 10.1093/embo-reports/kvf037. Epub 2002 Feb 15. EMBO Rep. 2002. PMID: 11850397 Free PMC article.

2

Cell cycle and genetic background dependence of the effect of loss of BRCA2 on ionizing radiation sensitivity.

Tutt A, Connor F, Bertwistle D, Kerr P, Peacock J, Ross G, Ashworth A. Tutt A, et al. Among authors: ashworth a. Oncogene. 2003 May 15;22(19):2926-31. doi: 10.1038/sj.onc.1206522. Oncogene. 2003. PMID: 12771943

3

DSS1 is required for RAD51 focus formation and genomic stability in mammalian cells.

Gudmundsdottir K, Lord CJ, Witt E, Tutt AN, Ashworth A. Gudmundsdottir K, et al. Among authors: ashworth a. EMBO Rep. 2004 Oct;5(10):989-93. doi: 10.1038/sj.embor.7400255. Epub 2004 Sep 10. EMBO Rep. 2004. PMID: 15359272 Free PMC article.

4

Mutation in Brca2 stimulates error-prone homology-directed repair of DNA double-strand breaks occurring between repeated sequences.

Tutt A, Bertwistle D, Valentine J, Gabriel A, Swift S, Ross G, Griffin C, Thacker J, Ashworth A. Tutt A, et al. Among authors: ashworth a. EMBO J. 2001 Sep 3;20(17):4704-16. doi: 10.1093/emboj/20.17.4704. EMBO J. 2001. PMID: 11532935 Free PMC article.

5

The relationship between the roles of BRCA genes in DNA repair and cancer predisposition.

Tutt A, Ashworth A. Tutt A, et al. Among authors: ashworth a. Trends Mol Med. 2002 Dec;8(12):571-6. doi: 10.1016/s1471-4914(02)02434-6. Trends Mol Med. 2002. PMID: 12470990 Review.

6

Close relatives or distant cousins?

Tutt A, Ashworth A. Tutt A, et al. Among authors: ashworth a. Lancet Oncol. 2003 Oct;4(10):593-4. doi: 10.1016/s1470-2045(03)01217-8. Lancet Oncol. 2003. PMID: 14554235 No abstract available.

7

Hallmarks of 'BRCAness' in sporadic cancers.

Turner N, Tutt A, Ashworth A. Turner N, et al. Among authors: ashworth a. Nat Rev Cancer. 2004 Oct;4(10):814-9. doi: 10.1038/nrc1457. Nat Rev Cancer. 2004. PMID: 15510162 Review.

8

Targeting the DNA repair defect of BRCA tumours.

Turner N, Tutt A, Ashworth A. Turner N, et al. Among authors: ashworth a. Curr Opin Pharmacol. 2005 Aug;5(4):388-93. doi: 10.1016/j.coph.2005.03.006. Curr Opin Pharmacol. 2005. PMID: 15955736 Review.

9

BRCA2-deficient CAPAN-1 cells are extremely sensitive to the inhibition of Poly (ADP-Ribose) polymerase: an issue of potency.

McCabe N, Lord CJ, Tutt AN, Martin NM, Smith GC, Ashworth A. McCabe N, et al. Among authors: ashworth a. Cancer Biol Ther. 2005 Sep;4(9):934-6. doi: 10.4161/cbt.4.9.2141. Epub 2005 Sep 1. Cancer Biol Ther. 2005. PMID: 16251802 Free article.

10

A synthetic lethal siRNA screen identifying genes mediating sensitivity to a PARP inhibitor.

Turner NC, Lord CJ, Iorns E, Brough R, Swift S, Elliott R, Rayter S, Tutt AN, Ashworth A. Turner NC, et al. Among authors: ashworth a. EMBO J. 2008 May 7;27(9):1368-77. doi: 10.1038/emboj.2008.61. Epub 2008 Apr 3. EMBO J. 2008. PMID: 18388863 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

848 results

Search Page

Filters