The calcium-binding sites of heparinase I from Flavobacterium heparinum are essential for enzymatic activity.
Liu D, Shriver Z, Godavarti R, Venkataraman G, Sasisekharan R.
Liu D, et al.
J Biol Chem. 1999 Feb 12;274(7):4089-95. doi: 10.1074/jbc.274.7.4089.
J Biol Chem. 1999.
PMID: 9933602
Free article.
In the accompanying paper (Shriver, Z., Liu, D., Hu, Y., and Sasisekharan, R. (1999) J. Biol. Chem. 274, 4082-4088), we have shown that calcium binds specifically to heparinase I and have identified two major calcium-binding sites (CB-1 and CB-2) that partly conform …
In the accompanying paper (Shriver, Z., Liu, D., Hu, Y., and Sasisekharan, R. (1999) J. Biol. Chem. 274, 4082-4088), we have s …