Johnston S - Search Results

1

Overexpression of BclXL in a human ovarian carcinoma cell line: paradoxic effects on chemosensitivity in vitro versus in vivo.

Rogers PM, Beale PJ, Al-Moundhri M, Boxall F, Patterson L, Valenti M, Raynaud F, Hobbs S, Johnston S, Kelland LR. Rogers PM, et al. Among authors: johnston s. Int J Cancer. 2002 Feb 20;97(6):858-63. doi: 10.1002/ijc.10132. Int J Cancer. 2002. PMID: 11857368

2

Comparison of estrogen receptor DNA binding in untreated and acquired antiestrogen-resistant human breast tumors.

Johnston SR, Lu B, Dowsett M, Liang X, Kaufmann M, Scott GK, Osborne CK, Benz CC. Johnston SR, et al. Cancer Res. 1997 Sep 1;57(17):3723-7. Cancer Res. 1997. PMID: 9288779

3

Farnesyl transferase inhibitors--a novel therapy for breast cancer.

Johnston SR, Kelland LR. Johnston SR, et al. Endocr Relat Cancer. 2001 Sep;8(3):227-35. doi: 10.1677/erc.0.0080227. Endocr Relat Cancer. 2001. PMID: 11566614 Review.

4

Preclinical antitumor activity and pharmacodynamic studies with the farnesyl protein transferase inhibitor R115777 in human breast cancer.

Kelland LR, Smith V, Valenti M, Patterson L, Clarke PA, Detre S, End D, Howes AJ, Dowsett M, Workman P, Johnston SR. Kelland LR, et al. Among authors: johnston sr. Clin Cancer Res. 2001 Nov;7(11):3544-50. Clin Cancer Res. 2001. PMID: 11705875

5

Phase II study of the efficacy and tolerability of two dosing regimens of the farnesyl transferase inhibitor, R115777, in advanced breast cancer.

Johnston SR, Hickish T, Ellis P, Houston S, Kelland L, Dowsett M, Salter J, Michiels B, Perez-Ruixo JJ, Palmer P, Howes A. Johnston SR, et al. J Clin Oncol. 2003 Jul 1;21(13):2492-9. doi: 10.1200/JCO.2003.10.064. J Clin Oncol. 2003. PMID: 12829668 Clinical Trial.

6

The farnesyltransferase inhibitor R115777 (tipifarnib) in combination with tamoxifen acts synergistically to inhibit MCF-7 breast cancer cell proliferation and cell cycle progression in vitro and in vivo.

Martin LA, Head JE, Pancholi S, Salter J, Quinn E, Detre S, Kaye S, Howes A, Dowsett M, Johnston SR. Martin LA, et al. Among authors: johnston sr. Mol Cancer Ther. 2007 Sep;6(9):2458-67. doi: 10.1158/1535-7163.MCT-06-0452. Mol Cancer Ther. 2007. PMID: 17876043

7

Exon 5 deletion variant estrogen receptor messenger RNA expression in relation to tamoxifen resistance and progesterone receptor/pS2 status in human breast cancer.

Daffada AA, Johnston SR, Smith IE, Detre S, King N, Dowsett M. Daffada AA, et al. Among authors: johnston sr. Cancer Res. 1995 Jan 15;55(2):288-93. Cancer Res. 1995. PMID: 7812959

8

Detre S, Salter J, Barnes DM, Riddler S, Hills M, Johnston SR, Gillett C, A'Hern R, Dowsett M. Detre S, et al. Among authors: johnston sr. Int J Cancer. 1999 Apr 12;81(2):309-13. doi: 10.1002/(sici)1097-0215(19990412)81:2<309::aid-ijc23>3.0.co;2-s. Int J Cancer. 1999. PMID: 10188736

9

BCAR1/p130Cas expression in untreated and acquired tamoxifen-resistant human breast carcinomas.

van der Flier S, Chan CM, Brinkman A, Smid M, Johnston SR, Dorssers LC, Dowsett M. van der Flier S, et al. Among authors: johnston sr. Int J Cancer. 2000 Sep 20;89(5):465-8. doi: 10.1002/1097-0215(20000920)89:5<465::aid-ijc11>3.0.co;2-o. Int J Cancer. 2000. PMID: 11008210

10

Integration of signal transduction inhibitors with endocrine therapy: an approach to overcoming hormone resistance in breast cancer.

Johnston SR, Head J, Pancholi S, Detre S, Martin LA, Smith IE, Dowsett M. Johnston SR, et al. Clin Cancer Res. 2003 Jan;9(1 Pt 2):524S-32S. Clin Cancer Res. 2003. PMID: 12538510 Review.

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