Sedivy JM - Search Results

1

Targeted inactivation of p53 in human cells does not result in aneuploidy.

Bunz F, Fauth C, Speicher MR, Dutriaux A, Sedivy JM, Kinzler KW, Vogelstein B, Lengauer C. Bunz F, et al. Among authors: sedivy jm. Cancer Res. 2002 Feb 15;62(4):1129-33. Cancer Res. 2002. PMID: 11861393

2

Requirement for p53 and p21 to sustain G2 arrest after DNA damage.

Bunz F, Dutriaux A, Lengauer C, Waldman T, Zhou S, Brown JP, Sedivy JM, Kinzler KW, Vogelstein B. Bunz F, et al. Among authors: sedivy jm. Science. 1998 Nov 20;282(5393):1497-501. doi: 10.1126/science.282.5393.1497. Science. 1998. PMID: 9822382

3

Somatic cell knockouts of tumor suppressor genes.

Hemmer R, Wei W, Dutriaux A, Sedivy J. Hemmer R, et al. Methods Mol Biol. 2003;223:187-206. doi: 10.1385/1-59259-329-1:187. Methods Mol Biol. 2003. PMID: 12777730 No abstract available.

4

Identification of CDK4 as a target of c-MYC.

Hermeking H, Rago C, Schuhmacher M, Li Q, Barrett JF, Obaya AJ, O'Connell BC, Mateyak MK, Tam W, Kohlhuber F, Dang CV, Sedivy JM, Eick D, Vogelstein B, Kinzler KW. Hermeking H, et al. Among authors: sedivy jm. Proc Natl Acad Sci U S A. 2000 Feb 29;97(5):2229-34. doi: 10.1073/pnas.050586197. Proc Natl Acad Sci U S A. 2000. PMID: 10688915 Free PMC article.

5

Real-time imaging of transcriptional activation in live cells reveals rapid up-regulation of the cyclin-dependent kinase inhibitor gene CDKN1A in replicative cellular senescence.

Herbig U, Wei W, Dutriaux A, Jobling WA, Sedivy JM. Herbig U, et al. Among authors: sedivy jm. Aging Cell. 2003 Dec;2(6):295-304. doi: 10.1046/j.1474-9728.2003.00067.x. Aging Cell. 2003. PMID: 14677632 Free article.

6

Gene targeting and somatic cell genetics--a rebirth or a coming of age?

Sedivy JM, Dutriaux A. Sedivy JM, et al. Trends Genet. 1999 Mar;15(3):88-90. doi: 10.1016/s0168-9525(98)01689-8. Trends Genet. 1999. PMID: 10203800 Review.

7

Loss of retinoblastoma but not p16 function allows bypass of replicative senescence in human fibroblasts.

Wei W, Herbig U, Wei S, Dutriaux A, Sedivy JM. Wei W, et al. Among authors: sedivy jm. EMBO Rep. 2003 Nov;4(11):1061-6. doi: 10.1038/sj.embor.embor7400001. Epub 2003 Oct 17. EMBO Rep. 2003. PMID: 14566323 Free PMC article.

8

Radiation-induced mutations at the autosomal thymidine kinase locus are not elevated in p53-null cells.

Chuang YY, Chen Q, Brown JP, Sedivy JM, Liber HL. Chuang YY, et al. Among authors: sedivy jm. Cancer Res. 1999 Jul 1;59(13):3073-6. Cancer Res. 1999. PMID: 10397247

9

A modest reduction in c-myc expression has minimal effects on cell growth and apoptosis but dramatically reduces susceptibility to Ras and Raf transformation.

Bazarov AV, Adachi S, Li SF, Mateyak MK, Wei S, Sedivy JM. Bazarov AV, et al. Among authors: sedivy jm. Cancer Res. 2001 Feb 1;61(3):1178-86. Cancer Res. 2001. PMID: 11221849

10

Molecular characterization of human telomerase reverse transcriptase-immortalized human fibroblasts by gene expression profiling: activation of the epiregulin gene.

Lindvall C, Hou M, Komurasaki T, Zheng C, Henriksson M, Sedivy JM, Björkholm M, Teh BT, Nordenskjöld M, Xu D. Lindvall C, et al. Among authors: sedivy jm. Cancer Res. 2003 Apr 15;63(8):1743-7. Cancer Res. 2003. PMID: 12702554

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