Broach JR - Search Results

1

A point mutation that confers constitutive activity to CXCR4 reveals that T140 is an inverse agonist and that AMD3100 and ALX40-4C are weak partial agonists.

Zhang WB, Navenot JM, Haribabu B, Tamamura H, Hiramatu K, Omagari A, Pei G, Manfredi JP, Fujii N, Broach JR, Peiper SC. Zhang WB, et al. Among authors: broach jr. J Biol Chem. 2002 Jul 5;277(27):24515-21. doi: 10.1074/jbc.M200889200. Epub 2002 Mar 28. J Biol Chem. 2002. PMID: 11923301 Free article.

2

Functional expression of CXCR4 in Saccharomyces cerevisiae in the development of powerful tools for the pharmacological characterization of CXCR4.

Wang ZX, Broach JR, Peiper SC. Wang ZX, et al. Among authors: broach jr. Methods Mol Biol. 2006;332:115-27. doi: 10.1385/1-59745-048-0:115. Methods Mol Biol. 2006. PMID: 16878688

3

Expression of CXCR4, a G-protein-coupled receptor for CXCL12 in yeast identification of new-generation inverse agonists.

Evans BJ, Wang Z, Broach JR, Oishi S, Fujii N, Peiper SC. Evans BJ, et al. Among authors: broach jr. Methods Enzymol. 2009;460:399-412. doi: 10.1016/S0076-6879(09)05220-3. Methods Enzymol. 2009. PMID: 19446737

4

Design and synthesis of downsized metastin (45-54) analogs with maintenance of high GPR54 agonistic activity.

Niida A, Wang Z, Tomita K, Oishi S, Tamamura H, Otaka A, Navenot JM, Broach JR, Peiper SC, Fujii N. Niida A, et al. Among authors: broach jr. Bioorg Med Chem Lett. 2006 Jan 1;16(1):134-7. doi: 10.1016/j.bmcl.2005.09.054. Epub 2005 Oct 18. Bioorg Med Chem Lett. 2006. PMID: 16242330

5

Genetic selection in Saccharomyces of mutant mammalian adenylyl cyclases with elevated basal activities.

Haney SA, Xu J, Lee SY, Ma CL, Duzic E, Broach JR, Manfredi JP. Haney SA, et al. Among authors: broach jr. Mol Genet Genomics. 2001 Aug;265(6):1120-8. doi: 10.1007/s004380100512. Mol Genet Genomics. 2001. PMID: 11523785

6

Yeast alpha mating factor structure-activity relationship derived from genetically selected peptide agonists and antagonists of Ste2p.

Manfredi JP, Klein C, Herrero JJ, Byrd DR, Trueheart J, Wiesler WT, Fowlkes DM, Broach JR. Manfredi JP, et al. Among authors: broach jr. Mol Cell Biol. 1996 Sep;16(9):4700-9. doi: 10.1128/MCB.16.9.4700. Mol Cell Biol. 1996. PMID: 8756627 Free PMC article.

7

Metastin and its variant forms suppress migration of pancreatic cancer cells.

Masui T, Doi R, Mori T, Toyoda E, Koizumi M, Kami K, Ito D, Peiper SC, Broach JR, Oishi S, Niida A, Fujii N, Imamura M. Masui T, et al. Among authors: broach jr. Biochem Biophys Res Commun. 2004 Feb 27;315(1):85-92. doi: 10.1016/j.bbrc.2004.01.021. Biochem Biophys Res Commun. 2004. PMID: 15013429

8

Identification of surrogate agonists for the human FPRL-1 receptor by autocrine selection in yeast.

Klein C, Paul JI, Sauvé K, Schmidt MM, Arcangeli L, Ransom J, Trueheart J, Manfredi JP, Broach JR, Murphy AJ. Klein C, et al. Among authors: broach jr. Nat Biotechnol. 1998 Dec;16(13):1334-7. doi: 10.1038/4310. Nat Biotechnol. 1998. PMID: 9853614

9

A yeast plasmid partitioning protein is a karyoskeletal component.

Wu LC, Fisher PA, Broach JR. Wu LC, et al. Among authors: broach jr. J Biol Chem. 1987 Jan 15;262(2):883-91. J Biol Chem. 1987. PMID: 3542994 Free article.

10

Cdc25p, the guanine nucleotide exchange factor for the Ras proteins of Saccharomyces cerevisiae, promotes exchange by stabilizing Ras in a nucleotide-free state.

Haney SA, Broach JR. Haney SA, et al. Among authors: broach jr. J Biol Chem. 1994 Jun 17;269(24):16541-8. J Biol Chem. 1994. PMID: 8206969 Free article.

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