Inactivation of cytochrome P450 by the food-derived complex phenol oleuropein.
Stupans I, Murray M, Kirlich A, Tuck KL, Hayball PJ.
Stupans I, et al.
Food Chem Toxicol. 2001 Nov;39(11):1119-24. doi: 10.1016/s0278-6915(01)00060-6.
Food Chem Toxicol. 2001.
PMID: 11527571
We have previously reported that oleuropein inhibits androstenedione 6 beta-hydroxylase activity, a CYP3A marker in human liver microsomes (Stupans, I., Stretch, G., Hayball, P., 2000. Olive oil phenols inhibit human hepatic microsomal activity. ...
We have previously reported that oleuropein inhibits androstenedione 6 beta-hydroxylase activity, a CYP3A marker in human liver microsomes ( …