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BET inhibitors (BETi) influence oxidative phosphorylation metabolism by affecting mitochondrial dynamics leading to alterations in apoptotic pathways in triple-negative breast cancer (TNBC) cells.
Rossi T, Iorio E, Chirico M, Pisanu ME, Amodio N, Cantafio MEG, Perrotta I, Colciaghi F, Fiorillo M, Gianferrari A, Puccio N, Neri A, Ciarrocchi A, Pistoni M. Rossi T, et al. Among authors: fiorillo m. Cell Prolif. 2024 Sep 2:e13730. doi: 10.1111/cpr.13730. Online ahead of print. Cell Prolif. 2024. PMID: 39223828
Loss of the tumour suppressor LKB1/STK11 uncovers a leptin-mediated sensitivity mechanism to mitochondrial uncouplers for targeted cancer therapy.
Angelopoulou A, Theocharous G, Valakos D, Polyzou A, Magkouta S, Myrianthopoulos V, Havaki S, Fiorillo M, Tremi I, Vachlas K, Nisotakis T, Thanos DF, Pantazaki A, Kletsas D, Bartek J, Petty R, Thanos D, McCrimmon RJ, Papaspyropoulos A, Gorgoulis VG. Angelopoulou A, et al. Among authors: fiorillo m. Mol Cancer. 2024 Jul 25;23(1):147. doi: 10.1186/s12943-024-02061-4. Mol Cancer. 2024. PMID: 39048991 Free PMC article.
174 results