Flores ER - Search Results

1

p63 and p73 are required for p53-dependent apoptosis in response to DNA damage.

Flores ER, Tsai KY, Crowley D, Sengupta S, Yang A, McKeon F, Jacks T. Flores ER, et al. Nature. 2002 Apr 4;416(6880):560-4. doi: 10.1038/416560a. Nature. 2002. PMID: 11932750

2

Role for the p53 homologue p73 in E2F-1-induced apoptosis.

Irwin M, Marin MC, Phillips AC, Seelan RS, Smith DI, Liu W, Flores ER, Tsai KY, Jacks T, Vousden KH, Kaelin WG Jr. Irwin M, et al. Among authors: flores er. Nature. 2000 Oct 5;407(6804):645-8. doi: 10.1038/35036614. Nature. 2000. PMID: 11034215

3

Targeted point mutations of p53 lead to dominant-negative inhibition of wild-type p53 function.

de Vries A, Flores ER, Miranda B, Hsieh HM, van Oostrom CT, Sage J, Jacks T. de Vries A, et al. Among authors: flores er. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2948-53. doi: 10.1073/pnas.052713099. Epub 2002 Feb 26. Proc Natl Acad Sci U S A. 2002. PMID: 11867759 Free PMC article.

4

Multiple response elements and differential p53 binding control Perp expression during apoptosis.

Reczek EE, Flores ER, Tsay AS, Attardi LD, Jacks T. Reczek EE, et al. Among authors: flores er. Mol Cancer Res. 2003 Dec;1(14):1048-57. Mol Cancer Res. 2003. PMID: 14707288

5

Tumor predisposition in mice mutant for p63 and p73: evidence for broader tumor suppressor functions for the p53 family.

Flores ER, Sengupta S, Miller JB, Newman JJ, Bronson R, Crowley D, Yang A, McKeon F, Jacks T. Flores ER, et al. Cancer Cell. 2005 Apr;7(4):363-73. doi: 10.1016/j.ccr.2005.02.019. Cancer Cell. 2005. PMID: 15837625 Free article.

6

The roles of p63 in cancer.

Flores ER. Flores ER. Cell Cycle. 2007 Feb 1;6(3):300-4. doi: 10.4161/cc.6.3.3793. Epub 2007 Feb 3. Cell Cycle. 2007. PMID: 17264676 Review.

7

TAp63 prevents premature aging by promoting adult stem cell maintenance.

Su X, Paris M, Gi YJ, Tsai KY, Cho MS, Lin YL, Biernaskie JA, Sinha S, Prives C, Pevny LH, Miller FD, Flores ER. Su X, et al. Among authors: flores er. Cell Stem Cell. 2009 Jul 2;5(1):64-75. doi: 10.1016/j.stem.2009.04.003. Cell Stem Cell. 2009. PMID: 19570515 Free PMC article.

8

p63 and p73 transcriptionally regulate genes involved in DNA repair.

Lin YL, Sengupta S, Gurdziel K, Bell GW, Jacks T, Flores ER. Lin YL, et al. Among authors: flores er. PLoS Genet. 2009 Oct;5(10):e1000680. doi: 10.1371/journal.pgen.1000680. Epub 2009 Oct 9. PLoS Genet. 2009. Retraction in: PLoS Genet. 2023 Mar 27;19(3):e1010699. doi: 10.1371/journal.pgen.1010699 PMID: 19816568 Free PMC article. Retracted.

9

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs.

Su X, Chakravarti D, Cho MS, Liu L, Gi YJ, Lin YL, Leung ML, El-Naggar A, Creighton CJ, Suraokar MB, Wistuba I, Flores ER. Su X, et al. Among authors: flores er. Nature. 2010 Oct 21;467(7318):986-90. doi: 10.1038/nature09459. Nature. 2010. PMID: 20962848 Free PMC article.

10

TAp63 is a master transcriptional regulator of lipid and glucose metabolism.

Su X, Gi YJ, Chakravarti D, Chan IL, Zhang A, Xia X, Tsai KY, Flores ER. Su X, et al. Among authors: flores er. Cell Metab. 2012 Oct 3;16(4):511-25. doi: 10.1016/j.cmet.2012.09.006. Cell Metab. 2012. PMID: 23040072 Free PMC article.

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