Bi K - Search Results

1

Translocation of PKC[theta] in T cells is mediated by a nonconventional, PI3-K- and Vav-dependent pathway, but does not absolutely require phospholipase C.

Villalba M, Bi K, Hu J, Altman Y, Bushway P, Reits E, Neefjes J, Baier G, Abraham RT, Altman A. Villalba M, et al. Among authors: bi k. J Cell Biol. 2002 Apr 15;157(2):253-63. doi: 10.1083/jcb.200201097. Epub 2002 Apr 15. J Cell Biol. 2002. PMID: 11956228 Free PMC article.

2

Membrane lipid microdomains and the role of PKCtheta in T cell activation.

Bi K, Altman A. Bi K, et al. Semin Immunol. 2001 Apr;13(2):139-46. doi: 10.1006/smim.2000.0305. Semin Immunol. 2001. PMID: 11308297 Review.

3

Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cells.

Villalba M, Bi K, Rodriguez F, Tanaka Y, Schoenberger S, Altman A. Villalba M, et al. Among authors: bi k. J Cell Biol. 2001 Oct 29;155(3):331-8. doi: 10.1083/jcb.200107080. Epub 2001 Oct 29. J Cell Biol. 2001. PMID: 11684704 Free PMC article.

4

SWAP-70-like adapter of T cells, an adapter protein that regulates early TCR-initiated signaling in Th2 lineage cells.

Tanaka Y, Bi K, Kitamura R, Hong S, Altman Y, Matsumoto A, Tabata H, Lebedeva S, Bushway PJ, Altman A. Tanaka Y, et al. Among authors: bi k. Immunity. 2003 Mar;18(3):403-14. doi: 10.1016/s1074-7613(03)00054-2. Immunity. 2003. PMID: 12648457 Free article.

5

Inhibition of the c-Jun N-terminal kinase/AP-1 and NF-kappaB pathways by PICOT, a novel protein kinase C-interacting protein with a thioredoxin homology domain.

Witte S, Villalba M, Bi K, Liu Y, Isakov N, Altman A. Witte S, et al. Among authors: bi k. J Biol Chem. 2000 Jan 21;275(3):1902-9. doi: 10.1074/jbc.275.3.1902. J Biol Chem. 2000. PMID: 10636891 Free article.

6

Antigen-induced translocation of PKC-theta to membrane rafts is required for T cell activation.

Bi K, Tanaka Y, Coudronniere N, Sugie K, Hong S, van Stipdonk MJ, Altman A. Bi K, et al. Nat Immunol. 2001 Jun;2(6):556-63. doi: 10.1038/88765. Nat Immunol. 2001. PMID: 11376344

7

Clustering of T cell ligands on artificial APC membranes influences T cell activation and protein kinase C theta translocation to the T cell plasma membrane.

Giannoni F, Barnett J, Bi K, Samodal R, Lanza P, Marchese P, Billetta R, Vita R, Klein MR, Prakken B, Kwok WW, Sercarz E, Altman A, Albani S. Giannoni F, et al. Among authors: bi k. J Immunol. 2005 Mar 15;174(6):3204-11. doi: 10.4049/jimmunol.174.6.3204. J Immunol. 2005. PMID: 15749850

8

BacMam-enabled LanthaScreen cellular assays for PI3K/Akt pathway compound profiling in disease-relevant cell backgrounds.

Carlson CB, Mashock MJ, Bi K. Carlson CB, et al. Among authors: bi k. J Biomol Screen. 2010 Mar;15(3):327-34. doi: 10.1177/1087057109357788. Epub 2010 Feb 9. J Biomol Screen. 2010. PMID: 20145103

9

Pharmacological inhibition of LRRK2 cellular phosphorylation sites provides insight into LRRK2 biology.

Zhao J, Hermanson SB, Carlson CB, Riddle SM, Vogel KW, Bi K, Nichols RJ. Zhao J, et al. Among authors: bi k. Biochem Soc Trans. 2012 Oct;40(5):1158-62. doi: 10.1042/BST20120137. Biochem Soc Trans. 2012. PMID: 22988882 Review.

10

Cellular LanthaScreen and beta-lactamase reporter assays for high-throughput screening of JAK2 inhibitors.

Robers MB, Machleidt T, Carlson CB, Bi K. Robers MB, et al. Among authors: bi k. Assay Drug Dev Technol. 2008 Aug;6(4):519-29. doi: 10.1089/adt.2008.144. Assay Drug Dev Technol. 2008. PMID: 18694336

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