Kliewer SA - Search Results

1

Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptors.

Moore LB, Maglich JM, McKee DD, Wisely B, Willson TM, Kliewer SA, Lambert MH, Moore JT. Moore LB, et al. Among authors: kliewer sa. Mol Endocrinol. 2002 May;16(5):977-86. doi: 10.1210/mend.16.5.0828. Mol Endocrinol. 2002. PMID: 11981033

2

Functional and structural comparison of PXR and CAR.

Moore JT, Moore LB, Maglich JM, Kliewer SA. Moore JT, et al. Among authors: kliewer sa. Biochim Biophys Acta. 2003 Feb 17;1619(3):235-8. doi: 10.1016/s0304-4165(02)00481-6. Biochim Biophys Acta. 2003. PMID: 12573482 Review.

3

Regulation of xenobiotic and bile acid metabolism by the nuclear pregnane X receptor.

Kliewer SA, Willson TM. Kliewer SA, et al. J Lipid Res. 2002 Mar;43(3):359-64. J Lipid Res. 2002. PMID: 11893771 Free article. Review.

4

PXR, CAR and drug metabolism.

Willson TM, Kliewer SA. Willson TM, et al. Among authors: kliewer sa. Nat Rev Drug Discov. 2002 Apr;1(4):259-66. doi: 10.1038/nrd753. Nat Rev Drug Discov. 2002. PMID: 12120277 Review.

5

Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification.

Maglich JM, Stoltz CM, Goodwin B, Hawkins-Brown D, Moore JT, Kliewer SA. Maglich JM, et al. Among authors: kliewer sa. Mol Pharmacol. 2002 Sep;62(3):638-46. doi: 10.1124/mol.62.3.638. Mol Pharmacol. 2002. PMID: 12181440

6

The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism.

Kliewer SA, Goodwin B, Willson TM. Kliewer SA, et al. Endocr Rev. 2002 Oct;23(5):687-702. doi: 10.1210/er.2001-0038. Endocr Rev. 2002. PMID: 12372848 Review.

7

Nuclear receptor regulation of genes involved in bile acid metabolism.

Moore JT, Goodwin B, Willson TM, Kliewer SA. Moore JT, et al. Among authors: kliewer sa. Crit Rev Eukaryot Gene Expr. 2002;12(2):119-35. doi: 10.1615/critreveukaryotgeneexpr.v12.i2.30. Crit Rev Eukaryot Gene Expr. 2002. PMID: 12434926 Review.

8

Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes.

Maglich JM, Parks DJ, Moore LB, Collins JL, Goodwin B, Billin AN, Stoltz CA, Kliewer SA, Lambert MH, Willson TM, Moore JT. Maglich JM, et al. Among authors: kliewer sa. J Biol Chem. 2003 May 9;278(19):17277-83. doi: 10.1074/jbc.M300138200. Epub 2003 Feb 27. J Biol Chem. 2003. PMID: 12611900 Free article.

9

Structural disorder in the complex of human pregnane X receptor and the macrolide antibiotic rifampicin.

Chrencik JE, Orans J, Moore LB, Xue Y, Peng L, Collins JL, Wisely GB, Lambert MH, Kliewer SA, Redinbo MR. Chrencik JE, et al. Among authors: kliewer sa. Mol Endocrinol. 2005 May;19(5):1125-34. doi: 10.1210/me.2004-0346. Epub 2005 Feb 10. Mol Endocrinol. 2005. PMID: 15705662

10

Crystal structure of the pregnane X receptor-estradiol complex provides insights into endobiotic recognition.

Xue Y, Moore LB, Orans J, Peng L, Bencharit S, Kliewer SA, Redinbo MR. Xue Y, et al. Among authors: kliewer sa. Mol Endocrinol. 2007 May;21(5):1028-38. doi: 10.1210/me.2006-0323. Epub 2007 Feb 27. Mol Endocrinol. 2007. PMID: 17327420

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